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结直肠癌继发疑似脉络膜转移的光动力疗法:文献综述

Photodynamic Therapy of Presumed Choroidal Metastasis Secondary to Colorectal Carcinoma: Literature Review.

作者信息

Biccas Neto Laurentino, Pulido José Z, Melo Gustavo B, Lima Luiz H, Rodrigues Eduardo B

机构信息

Ocular Oftalmologia, Vitória, Brazil.

Department of Oncology, Hospital Evangélico, Cachoeiro do Itapemirim, Brazil.

出版信息

Case Rep Ophthalmol Med. 2020 Jan 30;2020:6490535. doi: 10.1155/2020/6490535. eCollection 2020.

Abstract

Colorectal cancer may yield metastasis to the choroid. Its management may be challenging, since there is no consensus about treatment. We describe a case of a 70-year-old male with colon cancer who complained of worsening visual acuity of his better-seeing eye to 20/40 secondary to a nonpigmented choroidal mass of medium reflectivity under the inferior temporal arcade and neurosensory foveal detachment. Besides systemic chemotherapy, local treatment with verteporfin photodynamic therapy (vPDT) was performed. After one month, visual acuity improved to 20/25 and subretinal fluid faded. In conclusion, vPDT may be a useful adjuvant treatment modality for choroidal metastasis secondary to colorectal cancer.

摘要

结直肠癌可能会转移至脉络膜。其治疗可能具有挑战性,因为对于治疗尚无共识。我们描述了一例70岁男性结肠癌患者,其较好眼的视力恶化为20/40,原因是颞下弓下方有一个中等反射率的无色素脉络膜肿物以及神经感觉性黄斑脱离。除了全身化疗外,还进行了维替泊芬光动力疗法(vPDT)局部治疗。一个月后,视力提高到20/25,视网膜下液消退。总之,vPDT可能是结直肠癌继发脉络膜转移的一种有用的辅助治疗方式。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/22d7/7016402/56780ca671eb/CRIOPM2020-6490535.001.jpg

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