• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

尿路结石抑制剂与结石成核

Urolithiasis inhibitors and calculus nucleation.

作者信息

Grases F, Gil J J, Conte A

机构信息

Department of Chemistry, Faculty of Sciences, University of the Balears Islands, Spain.

出版信息

Urol Res. 1989;17(3):163-6. doi: 10.1007/BF00256244.

DOI:10.1007/BF00256244
PMID:2546313
Abstract

The possible inhibitors of heterogeneous nucleation were investigated. The effects of magnesium, pyrophosphate, citrate and Chondroitin Sulphate on calcium phosphate or uric acid heterogeneous nucleation of calcium oxalate were studied. It was found that whereas magnesium, pyrophosphate and citrate acted as effective inhibitors in the presence of calcium phosphate as heterogeneous nucleant, only chondroitin sulphate manifested important inhibitory effects when uric acid was the heterogeneous nucleant.

摘要

研究了异质成核的可能抑制剂。研究了镁、焦磷酸盐、柠檬酸盐和硫酸软骨素对草酸钙磷酸钙或尿酸异质成核的影响。结果发现,在磷酸钙作为异质成核剂存在的情况下,镁、焦磷酸盐和柠檬酸盐作为有效的抑制剂,而当尿酸作为异质成核剂时,只有硫酸软骨素表现出重要的抑制作用。

相似文献

1
Urolithiasis inhibitors and calculus nucleation.尿路结石抑制剂与结石成核
Urol Res. 1989;17(3):163-6. doi: 10.1007/BF00256244.
2
Inhibitory effect of pyrophosphate, citrate, magnesium and chondroitin sulphate in calcium oxalate urolithiasis.焦磷酸盐、柠檬酸盐、镁和硫酸软骨素在草酸钙尿路结石中的抑制作用。
Br J Urol. 1989 Sep;64(3):235-7. doi: 10.1111/j.1464-410x.1989.tb06004.x.
3
Glycosaminoglycans, uric acid and calcium oxalate urolithiasis.糖胺聚糖、尿酸与草酸钙尿路结石
Urol Res. 1991;19(6):375-80. doi: 10.1007/BF00310153.
4
Modulation of calcium oxalate monohydrate crystallization kinetics in vitro.一水合草酸钙体外结晶动力学的调控
Kidney Int. 1988 Sep;34(3):346-50. doi: 10.1038/ki.1988.187.
5
Modifiers of calcium oxalate crystallization found in urine. I. Studies with a continuous crystallizer using an artificial urine.尿液中草酸钙结晶的调节剂。I. 使用人工尿液的连续结晶器研究。
J Urol. 1986 Jun;135(6):1322-6. doi: 10.1016/s0022-5347(17)46084-8.
6
Inhibitors of calcium oxalate crystallization and urolithiasis.
Urol Int. 1992;48(4):409-14. doi: 10.1159/000282365.
7
Influence of urine on "in vitro" crystallization rate of calcium oxalate: determination of inhibitory activity by a [14C]oxalate technique.尿液对草酸钙“体外”结晶速率的影响:采用[¹⁴C]草酸盐技术测定抑制活性。
Clin Chim Acta. 1979 Oct 15;98(1-2):39-46. doi: 10.1016/0009-8981(79)90163-3.
8
The effect of some urinary stone inhibitors on membrane interaction potentials of stone crystals.某些尿路结石抑制剂对结石晶体膜相互作用电位的影响。
J Urol. 1987 Sep;138(3):557-62. doi: 10.1016/s0022-5347(17)43258-7.
9
Inhibitors of oxalocalcic lithiasis: effects of their interactions on calcium oxalate crystallization.草酸钙结石抑制剂:其相互作用对草酸钙结晶的影响。
Urology. 2012 Nov;80(5):1163.e13-8. doi: 10.1016/j.urology.2012.04.040. Epub 2012 Jun 27.
10
Influence of sodium pentosan polysulphate and certain inhibitors on calcium oxalate crystal growth.戊聚糖多硫酸酯钠及某些抑制剂对草酸钙晶体生长的影响。
Mol Cell Biochem. 1996 Mar 9;156(1):31-5. doi: 10.1007/BF00239316.

引用本文的文献

1
Isolation and purification of a new glycoprotein from human urine inhibiting calcium oxalate crystallization.从人尿中分离纯化一种抑制草酸钙结晶的新型糖蛋白。
Urol Res. 1993 Jan;21(1):61-6. doi: 10.1007/BF00295195.
2
The importance of crystallization processes in understanding of stone formation.
Urol Res. 1989;17(3):141. doi: 10.1007/BF00256240.
3
The relation between orthophosphate and pyrophosphate in normal subjects and in patients with urolithiasis.
Urol Res. 1989;17(3):173-5. doi: 10.1007/BF00256246.
4

本文引用的文献

1
Propensity for spontaneous nucleation of calcium oxalate. Quantitative assessment by urinary FPR-APR discriminant score.
Am J Med. 1980 Nov;69(5):681-9. doi: 10.1016/0002-9343(80)90418-0.
2
Urate does not influence the formation of calcium oxalate crystals in whole human urine at pH 5.3.
Clin Sci (Lond). 1982 Apr;62(4):421-5. doi: 10.1042/cs0620421.
3
Calcium phosphate formation in vitro. I. Factors affecting initial phase separation.
Arch Biochem Biophys. 1970 Oct;140(2):307-17. doi: 10.1016/0003-9861(70)90071-8.
4
Simple method for the study of heterogeneous nucleation in calcium oxalate urolithiasis.草酸钙尿路结石中异质成核研究的简易方法。
Glycosaminoglycans, uric acid and calcium oxalate urolithiasis.糖胺聚糖、尿酸与草酸钙尿路结石
Urol Res. 1991;19(6):375-80. doi: 10.1007/BF00310153.
5
Urolithiasis, inhibitors and promoters.尿石症、抑制剂与促进剂。
Urol Res. 1992;20(1):86-8. doi: 10.1007/BF00294344.
Br J Urol. 1988 Jun;61(6):468-73. doi: 10.1111/j.1464-410x.1988.tb05082.x.
5
The expectation of free and fixed particles in urinary stone disease.尿路结石病中游离和固定颗粒的预期情况。
Invest Urol. 1978 May;15(6):442-8.
6
Heterogeneous nucleation of calcium oxalate by seeds of monosodium urate.尿酸钠晶种引发草酸钙的异质成核作用。
Proc Soc Exp Biol Med. 1975 Sep;149(4):930-2. doi: 10.3181/00379727-149-38929.