Brown Andrew W, Ioannidis John P A, Cope Mark B, Bier Dennis M, Allison David B
Adv Nutr. 2014 Sep;5(5):563-5. doi: 10.3945/an.114.006577.
Humans interact with food daily. Such repeated exposure creates a widespread, superficial familiarity with nutrition. Personal familiarity with nutrition from individual and cultural perspectives may give rise to beliefs about food not grounded in scientific evidence. In this summary of the session entitled “Unscientific Beliefs about Scientific Topics in Nutrition,” we discuss accumulated work illustrating and quantifying potentially misleading practices in the conduct and, more so, reporting of nutrition science along with proposed approaches to amelioration. We begin by defining “unscientific beliefs” and from where such beliefs may come, followed by discussing how large bodies of nutritional epidemiologic observations not only create highly improbable patterns of association but implausible magnitudes of implied effect. Poor reporting practices, biases, and methodologic issues that have distorted scientific understandings of nutrition are presented, followed by potential influences of conflicts of interest that extend beyond financial considerations. We conclude with recommendations for improving the conduct, reporting, and communication of nutrition-related research to ground discussions in evidence rather than solely on beliefs.
人类每天都与食物相互作用。这种反复接触会产生对营养广泛而肤浅的熟悉感。从个人和文化角度对营养的个人熟悉感可能会引发一些关于食物的信念,而这些信念并非基于科学证据。在本次题为“关于营养科学主题的非科学信念”的会议总结中,我们讨论了一系列积累的工作,这些工作阐明并量化了在营养科学的开展过程中,尤其是在报告方面可能产生误导的做法,以及提出的改善方法。我们首先定义“非科学信念”及其可能的来源,接着讨论大量营养流行病学观察结果如何不仅产生极不可能的关联模式,而且产生难以置信的隐含效应大小。我们还将介绍那些扭曲了对营养科学理解的不良报告做法、偏差和方法学问题,以及超出财务考量的利益冲突的潜在影响。最后,我们给出了一些建议,以改进营养相关研究的开展、报告和交流,使讨论基于证据而非仅仅基于信念。