继续下蛋吧，妈妈，用RNA干扰赶走我生殖衰老的忧郁。 - Suppr

Keep on laying eggs Mama, RNAi my reproductive aging blues away.

作者信息

Kumar Sandeep, Kocsisova Zuzana, Kornfeld Kerry

机构信息

Department of Developmental Biology, Washington University School of Medicine, St. Louis, Missouri, United States of America.

出版信息

PLoS Genet. 2014 Dec 4;10(12):e1004808. doi: 10.1371/journal.pgen.1004808. eCollection 2014 Dec.

DOI:10.1371/journal.pgen.1004808

PMID:25474201

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4256258/

Abstract

摘要

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2a3f/4256258/ddd1d8cb05d6/pgen.1004808.g001.jpg

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本文引用的文献

Gene pathways that delay Caenorhabditis elegans reproductive senescence.延缓秀丽隐杆线虫生殖衰老的基因通路。

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Identification of mutations that delay somatic or reproductive aging of Caenorhabditis elegans.鉴定延迟秀丽隐杆线虫体细胞或生殖衰老的突变。

Genetics. 2011 Sep;189(1):341-56. doi: 10.1534/genetics.111.130450. Epub 2011 Jul 12.

TGF-β and insulin signaling regulate reproductive aging via oocyte and germline quality maintenance.TGF-β 和胰岛素信号通过卵母细胞和生殖细胞质量维持来调节生殖衰老。

Cell. 2010 Oct 15;143(2):299-312. doi: 10.1016/j.cell.2010.09.013.

The genetics of ageing.衰老的遗传学。

Nature. 2010 Mar 25;464(7288):504-12. doi: 10.1038/nature08980.

Developmental biomarkers of aging in Caenorhabditis elegans.衰老的秀丽隐杆线虫发育生物标志物。

Dev Dyn. 2010 May;239(5):1306-14. doi: 10.1002/dvdy.22224.

TGF-beta Sma/Mab signaling mutations uncouple reproductive aging from somatic aging.TGF-β Sma/Mab 信号通路突变可使生殖衰老与躯体衰老脱耦。

PLoS Genet. 2009 Dec;5(12):e1000789. doi: 10.1371/journal.pgen.1000789. Epub 2009 Dec 24.

Genetics of reproductive lifespan.生殖寿命的遗传学

Nat Genet. 2009 Jun;41(6):637-8. doi: 10.1038/ng0609-637.

The measurement and analysis of age-related changes in Caenorhabditis elegans.秀丽隐杆线虫年龄相关变化的测量与分析。

WormBook. 2008 Jan 24:1-21. doi: 10.1895/wormbook.1.137.1.

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Keep on laying eggs Mama, RNAi my reproductive aging blues away.

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