Graduate Program in Health and Development in the Central-West Region of Brazil, Federal University of Mato Grosso do Sul-UFMS, 79070-900 Campo Grande, Brazil.
Graduate of Pharmaceutical Sciences, Federal University of Mato Grosso do Sul-UFMS, 79070-900 Campo Grande, Brazil.
Molecules. 2020 Oct 1;25(19):4513. doi: 10.3390/molecules25194513.
is a genus of Clusiaceae, distributed throughout tropical Asia, Africa, New Caledonia, Polynesia, and Brazil. plants contain a broad range of biologically active metabolites which, in the last few decades, have received considerable attention due to the chemical compositions of their extracts, with compounds which have been shown to have beneficial effects in several diseases. Our work had the objective of reviewing the benefits of five species (, , , , and ). These species provide a rich natural source of bioactive compounds with relevant therapeutic properties and anti-inflammatory effects, such as for the treatment of skin disorders, wounds, pain, and infections, having demonstrated antinociceptive, antioxidant, antitumoral, antifungal, anticancer, antihistaminic, antiulcerogenic, antimicrobial, antiviral, vasodilator, hypolipidemic, hepatoprotective, nephroprotective, and cardioprotective properties. This demonstrates the relevance of the genus as a rich source of compounds with valuable therapeutic properties, with potential use in the prevention and treatment of nontransmissible chronic diseases.
是藤黄科的一个属，分布于热带亚洲、非洲、新喀里多尼亚、波利尼西亚和巴西。该属植物含有广泛的具有生物活性的代谢物，在过去几十年中，由于其提取物的化学成分，这些代谢物引起了相当大的关注，其中一些化合物已被证明对多种疾病具有有益的影响。我们的工作旨在综述五个 物种（ 、 、 、 和 ）的益处。这些物种为具有相关治疗特性和抗炎作用的生物活性化合物提供了丰富的天然来源，例如用于治疗皮肤疾病、创伤、疼痛和感染，已表现出镇痛、抗氧化、抗肿瘤、抗真菌、抗癌、抗组胺、抗溃疡、抗菌、抗病毒、血管舒张、降血脂、保肝、保肾和心脏保护特性。这表明该属作为具有有价值治疗特性的化合物的丰富来源具有相关性，具有预防和治疗非传染性慢性疾病的潜力。
