Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, P.O. Box 2871, Beijing 100085, China.
Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, P.O. Box 2871, Beijing 100085, China.
Chemosphere. 2015 Feb;121:92-100. doi: 10.1016/j.chemosphere.2014.11.034. Epub 2014 Dec 2.
A double membrane system comprising a membrane bioreactor (MBR) combined with a nanofiltration (NF) membrane was investigated on a pilot scale for the treatment of antibiotic production wastewater over a three-month period at a pharmaceutical company in Wuxi, China. By recycling the NF concentrate, the combined MBR-NF process was shown to be effective for the treatment of antibiotic production wastewater, resulting in excellent water quality and a high water yield of 92±5.6%. The water quality of the pilot-scale MBR-NF process was excellent; e.g., the concentrations of TOC, NH4(+)-N, TP were stable at 5.52, 0.68, 0.34 mg L(-1), respectively, and the values of turbidity and conductivity of the NF permeate were 0.15 NTU and 2.5 mS cm(-1), respectively; these values meet China's water quality standard requirements for industrial use (GB21903-2008). Not only were the antibiotic removal rates of spiramycin (SPM) and new spiramycin (NSPM) over 95%, the acute toxicity was also drastically reduced by the MBR-NF pilot system. The main organics in the MBR effluent were proteins, polysaccharides, and humic-like substances; they were almost completely retained by the NF membrane and further biodegraded in the MBR because the NF concentrate was recycled. The microbial community of the MBR did not significantly change with the recycling of the NF concentrate.
在中国无锡的一家制药公司，采用中试规模的膜生物反应器（MBR）与纳滤（NF）膜组合的双膜系统，对处理抗生素生产废水进行了为期三个月的研究。通过回收 NF 浓缩液，MBR-NF 组合工艺被证明可有效处理抗生素生产废水，得到了优异的水质和 92±5.6%的高产水率。中试规模 MBR-NF 工艺的水质非常好；例如，TOC、NH4(+)-N、TP 的浓度分别稳定在 5.52、0.68、0.34mg/L，NF 透过液的浊度和电导率分别为 0.15NTU 和 2.5mS/cm；这些值均符合中国工业用水水质标准（GB21903-2008）。螺旋霉素（SPM）和新螺旋霉素（NSPM）的抗生素去除率均超过 95%，并且 MBR-NF 中试系统大大降低了急性毒性。MBR 出水中的主要有机物为蛋白质、多糖和类腐殖质物质；由于回收 NF 浓缩液，它们几乎被 NF 膜完全截留，并在 MBR 中进一步生物降解。由于回收 NF 浓缩液，MBR 的微生物群落没有明显变化。
