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牙线和氯己定漱口水作为刷牙辅助手段在去除牙菌斑和牙龈炎症方面的疗效——一项三向交叉试验

Efficacy of dental floss and chlorhexidine mouth rinse as an adjunct to toothbrushing in removing plaque and gingival inflammation - a three way cross over trial.

作者信息

Arora Vikram, Tangade Pradeep, T L Ravishankar, Tirth Amit, Pal Sumit, Tandon Vaibhav

机构信息

Post Graduate Student, Department of Public Health Dentistry, Kothiwal Dental College and Research Centre , Moradabad, India .

Professor & Head, Department of Public Health Dentistry, Kothiwal Dental College and Research Centre , Moradabad, India .

出版信息

J Clin Diagn Res. 2014 Oct;8(10):ZC01-4. doi: 10.7860/JCDR/2014/8807.4943. Epub 2014 Oct 20.

Abstract

BACKGROUND

Maintaining good oral hygiene is important to combat periodontal diseases. The use of tooth brush alone does not serve the purpose of removing plaque which demands the use of some adjuncts such as proximal cleaning aids.

AIM

The study was conducted to compare the efficacy of Dental Floss and 0.12% Chlorhexidine Gluconate Mouthrinse as an adjunct to toothbrushing on plaque accumulation and gingival inflammation.

SETTINGS AND DESIGN

Department of Public Health Dentistry, Kothiwal Dental College and Research Centre, Moradabad, India. This was a randomized, double blind, three-way cross over clinical trial.

MATERIALS AND METHODS

Forty five dental students in the age group of 19-25yr. were enrolled into the study. Subjects were randomly assigned into three groups (n=15) i.e. Group A- Toothbrushing with Dental floss (TB+DF), Group B- Toothbrushing with 0.12% Chlorhexidine Gluconate Mouthrinse (TB+CHX-MR) and Group C- Toothbrushing alone (TB Alone) in a three-way crossover manner. After 21 d of trial period, plaque index (PI) and gingival index (GI) were assessed for each group, oral prophylaxis followed by a washout period for 14d.

STATISTICAL ANALYSIS USED

Mean, standard deviations and p-values were obtained. ANOVA test was used to compare the intergroup difference and Post hoc test to compare between the two groups.

RESULTS

The inter-group comparison for GI and PI at all interventions showed statistically significant difference (p<0.001). While comparing between group A and group C at second and third follow up, no significant difference were observed though group A showed reduction in mean values for both the clinical parameters whereas while comparing between group A and group B, statistically significant difference was observed, which is in line when compared with group B and group C. The Group B showed more reduction in plaque and gingival scores which was found to be statistically significant (p<0.001).

CONCLUSION

CHX-MR when used as an adjunct to toothbrushing is more effective in the reduction of plaque and gingival scores than a toothbrush alone or in combination with DF.

摘要

背景

保持良好的口腔卫生对于对抗牙周疾病很重要。仅使用牙刷无法达到清除牙菌斑的目的,这需要使用一些辅助工具,如牙间隙清洁辅助工具。

目的

本研究旨在比较牙线和0.12%葡萄糖酸氯己定漱口水作为刷牙辅助工具对牙菌斑积聚和牙龈炎症的效果。

设置与设计

印度莫拉达巴德科蒂瓦尔牙科学院和研究中心公共卫生牙科学系。这是一项随机、双盲、三交叉临床试验。

材料与方法

招募了45名年龄在19 - 25岁的牙科学生参与研究。受试者被随机分为三组(n = 15),即A组 - 刷牙加牙线(TB + DF),B组 - 刷牙加0.12%葡萄糖酸氯己定漱口水(TB + CHX - MR),C组 - 仅刷牙(仅TB),采用三交叉方式。在21天的试验期后,评估每组的菌斑指数(PI)和牙龈指数(GI),进行口腔预防,随后有14天的洗脱期。

使用的统计分析

获得均值、标准差和p值。使用方差分析测试比较组间差异,并使用事后检验比较两组之间的差异。

结果

所有干预措施下GI和PI的组间比较显示出统计学显著差异(p < 0.001)。在第二次和第三次随访时比较A组和C组,未观察到显著差异,尽管A组的两个临床参数均值均有所降低;而在比较A组和B组时,观察到统计学显著差异,与B组和C组比较时情况相符。B组的菌斑和牙龈评分降低更多,差异具有统计学意义(p < 0.001)。

结论

当作为刷牙的辅助工具使用时,葡萄糖酸氯己定漱口水在降低菌斑和牙龈评分方面比单独使用牙刷或牙刷与牙线联合使用更有效。

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