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五味子科三萜类化合物:最新研究进展。

Triterpenoids from the Schisandraceae family: an update.

机构信息

State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, Yunnan, P. R. China.

出版信息

Nat Prod Rep. 2015 Mar;32(3):367-410. doi: 10.1039/c4np00117f.

Abstract

Several significant advances in the field of phytochemistry were made between 2008 and 2014 because of the high level of interest in Schisandraceae triterpenoids. In addition to a dramatic increase in the number of newly identified triterpenoids, the first complete synthesis of a schinortriterpenoid was accomplished. There has also been substantial progress in investigations of biological activity and mechanism of action. In this update, we review more than 250 new triterpenoids and describe their structures, classifications, biogenetic pathways, syntheses, and bioactivities.

摘要

由于对五味子科三萜类化合物的高度关注,2008 年至 2014 年期间,植物化学领域取得了几项重大进展。除了新鉴定的三萜数量急剧增加外,还完成了第一个岩白菜素三萜的全合成。在生物活性和作用机制的研究方面也取得了实质性进展。在本次更新中,我们综述了 250 多种新的三萜类化合物,并描述了它们的结构、分类、生物合成途径、合成和生物活性。

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