神经发育中发育线索的时空整合
Spatiotemporal integration of developmental cues in neural development.
作者信息
Borodinsky Laura N, Belgacem Yesser H, Swapna Immani, Visina Olesya, Balashova Olga A, Sequerra Eduardo B, Tu Michelle K, Levin Jacqueline B, Spencer Kira A, Castro Patricio A, Hamilton Andrew M, Shim Sangwoo
机构信息
Department of Physiology & Membrane Biology and Institute for Pediatric Regenerative Medicine, Shriners Hospital for Children Northern California, University of California Davis School of Medicine, Sacramento, California, 95817.
出版信息
Dev Neurobiol. 2015 Apr;75(4):349-59. doi: 10.1002/dneu.22254. Epub 2014 Dec 10.
Abstract
Nervous system development relies on the generation of neurons, their differentiation and establishment of synaptic connections. These events exhibit remarkable plasticity and are regulated by many developmental cues. Here, we review the mechanisms of three classes of these cues: morphogenetic proteins, electrical activity, and the environment. We focus on second messenger dynamics and their role as integrators of the action of diverse cues, enabling plasticity in the process of neural development.
摘要
神经系统的发育依赖于神经元的生成、分化以及突触连接的建立。这些过程具有显著的可塑性，并受到多种发育信号的调控。在此，我们综述三类此类信号的作用机制：形态发生蛋白、电活动和环境因素。我们着重探讨第二信使动力学及其作为多种信号作用整合者的角色，这使得神经发育过程具有可塑性。
相似文献
1
Spatiotemporal integration of developmental cues in neural development.神经发育中发育线索的时空整合
Dev Neurobiol. 2015 Apr;75(4):349-59. doi: 10.1002/dneu.22254. Epub 2014 Dec 10.
2
Control of neuronal ploidy during vertebrate development.脊椎动物发育过程中神经元倍性的调控。
Results Probl Cell Differ. 2011;53:547-63. doi: 10.1007/978-3-642-19065-0_22.
3
From cradle to grave: the multiple roles of fibroblast growth factors in neural development.从摇篮到坟墓：成纤维细胞生长因子在神经发育中的多重作用。
Neuron. 2011 Aug 25;71(4):574-88. doi: 10.1016/j.neuron.2011.08.002.
4
Early neural development in vertebrates is also a matter of calcium.脊椎动物的早期神经发育也与钙有关。
Biochimie. 2011 Dec;93(12):2102-11. doi: 10.1016/j.biochi.2011.06.032. Epub 2011 Jul 3.
5
Mitochondria in Developmental and Adult Neurogenesis.线粒体在发育和成年神经发生中的作用。
Neurotox Res. 2019 Aug;36(2):257-267. doi: 10.1007/s12640-018-9942-y. Epub 2018 Sep 13.
6
Crosstalk among electrical activity, trophic factors and morphogenetic proteins in the regulation of neurotransmitter phenotype specification.电活动、营养因子和形态发生蛋白在神经递质表型特化调控中的相互作用。
J Chem Neuroanat. 2016 Apr;73:3-8. doi: 10.1016/j.jchemneu.2015.12.001. Epub 2015 Dec 12.
7
PSA-NCAM in mammalian structural plasticity and neurogenesis.哺乳动物结构可塑性和神经发生中的多唾液酸神经细胞黏附分子
Prog Neurobiol. 2006 Oct;80(3):129-64. doi: 10.1016/j.pneurobio.2006.08.003. Epub 2006 Oct 9.
8
Adult neural stem cells: plastic or restricted neuronal fates?成体神经干细胞：可塑性还是受限的神经元命运？
Development. 2013 Aug;140(16):3303-9. doi: 10.1242/dev.093096.
9
CREB signalling regulates early survival, neuronal gene expression and morphological development in adult subventricular zone neurogenesis.CREB 信号转导调节成年侧脑室下区神经发生中的早期存活、神经元基因表达和形态发育。
Mol Cell Neurosci. 2011 Jan;46(1):79-88. doi: 10.1016/j.mcn.2010.08.008. Epub 2010 Aug 27.
10
Pro-neural factors and neurogenesis.神经前体细胞因子与神经发生
Dev Dyn. 2005 Nov;234(3):808-13. doi: 10.1002/dvdy.20522.
引用本文的文献
1
Lamin A/C regulates cerebellar granule cell maturation.核纤层蛋白A/C调节小脑颗粒细胞成熟。
Cell Biol Toxicol. 2025 Apr 5;41(1):66. doi: 10.1007/s10565-025-10011-z.
2
A Computational Approach to Explaining Bioelectrically Induced Persistent, Stochastic Changes of Axial Polarity in Planarian Regeneration.一种解释生物电诱导涡虫再生过程中轴向极性持续、随机变化的计算方法。
Bioelectricity. 2022 Mar 15;4(1):18-30. doi: 10.1089/bioe.2021.0036. eCollection 2022 Mar.
3
Conductive gradient hydrogels allow spatial control of adult stem cell fate.导电梯度水凝胶可实现对成年干细胞命运的空间控制。
J Mater Chem B. 2024 Feb 14;12(7):1854-1863. doi: 10.1039/d3tb02269b.
4
Netrin-1 Stimulates Migration of Neogenin Expressing Aggressive Melanoma Cells.神经导向因子 1 促进神经导向因子受体表达的侵袭性黑素瘤细胞的迁移。
Int J Mol Sci. 2022 Oct 22;23(21):12751. doi: 10.3390/ijms232112751.
5
A Neurodevelopmental Perspective for Autism-Associated Gene Function.自闭症相关基因功能的神经发育视角
OBM Neurobiol. 2017;1(2). doi: 10.21926/obm.neurobiol.1702004. Epub 2017 Apr 25.
6
From Neural Tube Formation Through the Differentiation of Spinal Cord Neurons: Ion Channels in Action During Neural Development.从神经管形成到脊髓神经元分化：神经发育过程中起作用的离子通道
Front Mol Neurosci. 2020 Apr 24;13:62. doi: 10.3389/fnmol.2020.00062. eCollection 2020.
7
Neurexin-1α regulates neurite growth of rat hippocampal neurons.神经纤毛蛋白-1α调节大鼠海马神经元的轴突生长。
Int J Physiol Pathophysiol Pharmacol. 2019 Aug 15;11(4):115-125. eCollection 2019.
8
Dynamic intercellular transport modulates the spatial patterning of differentiation during early neural commitment.动态细胞间运输调节早期神经特化过程中的分化空间模式。
Nat Commun. 2018 Oct 5;9(1):4111. doi: 10.1038/s41467-018-06693-1.
9
as a Model Organism for the Study of Spinal Cord Formation, Development, Function and Regeneration.作为研究脊髓形成、发育、功能和再生的模式生物。
Front Neural Circuits. 2017 Nov 23;11:90. doi: 10.3389/fncir.2017.00090. eCollection 2017.
10
Endogenous Bioelectric Signaling Networks: Exploiting Voltage Gradients for Control of Growth and Form.内源性生物电信号网络：利用电压梯度控制生长和形态。
Annu Rev Biomed Eng. 2017 Jun 21;19:353-387. doi: 10.1146/annurev-bioeng-071114-040647.
本文引用的文献
1
Non-cell-autonomous mechanism of activity-dependent neurotransmitter switching.活性依赖型神经递质转换的非细胞自主机制
Neuron. 2014 Jun 4;82(5):1004-16. doi: 10.1016/j.neuron.2014.04.029.
2
Signaling mechanisms of non-conventional axon guidance cues: the Shh, BMP and Wnt morphogens.非传统轴突导向线索的信号机制：Shh、BMP 和 Wnt 形态发生素。
Curr Opin Neurobiol. 2013 Dec;23(6):965-73. doi: 10.1016/j.conb.2013.09.002. Epub 2013 Oct 29.
3
Oscillatory control of factors determining multipotency and fate in mouse neural progenitors.振荡控制决定小鼠神经祖细胞多能性和命运的因素。
Science. 2013 Dec 6;342(6163):1203-8. doi: 10.1126/science.1242366. Epub 2013 Oct 31.
4
Optogenetic-mediated increases in in vivo spontaneous activity disrupt pool-specific but not dorsal-ventral motoneuron pathfinding.光遗传学介导的体内自发活动增加扰乱了特定神经元池但不扰乱背腹运动神经元的投射。
Proc Natl Acad Sci U S A. 2013 Oct 22;110(43):17528-33. doi: 10.1073/pnas.1316457110. Epub 2013 Oct 7.
5
The mechanisms of Hedgehog signalling and its roles in development and disease.Hedgehog 信号通路的机制及其在发育和疾病中的作用。
Nat Rev Mol Cell Biol. 2013 Jul;14(7):416-29. doi: 10.1038/nrm3598. Epub 2013 May 30.
6
BMP signaling specifies the development of a large and fast CNS synapse.BMP 信号指定了一个大而快速的中枢神经系统突触的发育。
Nat Neurosci. 2013 Jul;16(7):856-64. doi: 10.1038/nn.3414. Epub 2013 May 26.
7
Dopamine from the brain promotes spinal motor neuron generation during development and adult regeneration.大脑中的多巴胺在发育过程和成年再生中促进脊髓运动神经元的产生。
Dev Cell. 2013 Jun 10;25(5):478-91. doi: 10.1016/j.devcel.2013.04.012. Epub 2013 May 23.
8
Specified neural progenitors sort to form sharp domains after noisy Shh signaling.特定的神经祖细胞在嘈杂的 Shh 信号后会进行排序，形成清晰的域。
Cell. 2013 Apr 25;153(3):550-61. doi: 10.1016/j.cell.2013.03.023.
9
Neurotransmitter switching in the adult brain regulates behavior.成年人大脑中的神经递质转换调节行为。
Science. 2013 Apr 26;340(6131):449-53. doi: 10.1126/science.1234152.
10
GLI activation by atypical protein kinase C ι/λ regulates the growth of basal cell carcinomas.非典型蛋白激酶 Cι/λ 对 GLI 的激活调控基底细胞癌的生长。
Nature. 2013 Feb 28;494(7438):484-8. doi: 10.1038/nature11889.
Zotero 插件