Schwab Fabienne Dominique, Huang Dorothy Jane, Schmid Seraina Margaretha, Schötzau Andreas, Güth Uwe
University Hospital Basel (UHB), Department of Gynecology and Obstetrics, Spitalstrasse 21, CH-4031 Basel, Switzerland.
Spital Grabs, Department of Gynecology & Obsterics, Spitalstrasse 44, CH-9472 Grabs, Switzerland.
Breast. 2015 Feb;24(1):90-2. doi: 10.1016/j.breast.2014.11.008. Epub 2014 Dec 4.
This is the first comprehensive analysis comparing specific aspects of tumor detection between the two "traditional" breast cancer detection methods self-detection (SD) and clinical breast examination (CBE). a) Which method is better in detecting smaller tumors? Both methods showed similar mean tumor diameters (SD: 22.1 mm vs. CBE: 21.9 mm; p = 0.991). b) Different frequency distributions of tumor locations would indicate that certain locations in the breast are more difficult to palpate: comparison of both methods showed comparable results (p = 0.835). c) General differences in tumor sizes with regard to certain locations would be of importance because the patients and/or the physicians could be educated to pay particular attention to certain locations during physical examination, where larger tumors tend to be found: tumors located in the central region were with 25.0 mm significantly larger than those in the peripheral regions of the breast (superior: 21.6 mm, p = 0.001; inferior: 21.6 mm, p = 0.015; lateral: 21.9 mm, p = 0.002; medial (20.9 mm, p = 0.001). Tumor sizes within the four peripheral regions did not differ significantly. d) Patients whose tumors were found by CBE were older than those whose tumors were found by SD (67 years vs. 60 years, p < 0.001).
annual CBE should be an integral part of general medical care in older women.
这是首次对两种“传统”乳腺癌检测方法即自我检测（SD）和临床乳腺检查（CBE）在肿瘤检测的特定方面进行的全面分析。a）哪种方法在检测较小肿瘤方面更好？两种方法显示出相似的平均肿瘤直径（SD：22.1毫米 vs. CBE：21.9毫米；p = 0.991）。b）肿瘤位置的不同频率分布表明乳腺中的某些位置更难触诊：两种方法的比较显示结果相当（p = 0.835）。c）某些位置的肿瘤大小的总体差异很重要，因为可以对患者和/或医生进行教育，使其在体格检查期间特别关注某些位置，在这些位置往往能发现较大的肿瘤：位于中央区域的肿瘤为25.0毫米，明显大于乳腺周边区域的肿瘤（上部：21.6毫米，p = 0.001；下部：21.6毫米，p = 0.015；外侧：21.9毫米，p = 0.002；内侧：20.9毫米，p = 0.001）。四个周边区域内的肿瘤大小无显著差异。d）通过CBE发现肿瘤的患者比通过SD发现肿瘤的患者年龄更大（67岁 vs. 60岁，p < 0.001）。
年度CBE应成为老年女性常规医疗保健的一个组成部分。
