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对于有宫颈锥切史且宫颈短的患者,早期使用宫颈托治疗是否可行?

Is Early Treatment with a Cervical Pessary an Option in Patients with a History of Surgical Conisation and a Short Cervix?

作者信息

Kyvernitakis I, Khatib R, Stricker N, Arabin B

机构信息

Department of Gynecology and Obstetrics, Philipps-University of Marburg, Marburg , in cooperation with the Clara Angela Foundation, Witten.

出版信息

Geburtshilfe Frauenheilkd. 2014 Nov;74(11):1003-1008. doi: 10.1055/s-0034-1383271.

DOI:10.1055/s-0034-1383271
PMID:25484374
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4245249/
Abstract

Patients with a history of one or more conizations have an increased risk of spontaneous preterm birth (SPTB). The aim of this study was to investigate the outcome of pregnancies in patients with a history of conization and early treatment with a cervical pessary. In this pilot observational study we included 21 patients and evaluated the obstetric history, the interval between pessary placement and delivery, gestational age at delivery, the neonatal outcome and the number of days of maternal and neonatal admission. Among the study group of 21 patients, 20 patients had a singleton and one had a dichorionic/diamniotic twin pregnancy. At insertion, the mean gestational age was 17 + 2 (10 + 5-24 + 0) weeks and the mean cervical length was 19 (4-36) mm. Six patients presented with funneling at insertion with a mean funneling width of 19.7 (10-38) mm and funneling length of 19.9 (10-37) mm. Five patients had already lost at least one child due to early spontaneous preterm birth and another five had at least one previous abortion, who have now delivered beyond 34 weeks. The mean gestational age at delivery was 38 (31 + 1-41 + 0) gestational weeks and the mean interval between insertion and delivery was 145 (87-182) days. Our findings suggest a beneficial effect of an early pessary placement for patients at high-risk for preterm birth due to conization.

摘要

有过一次或多次宫颈锥切术病史的患者发生自发性早产(SPTB)的风险增加。本研究的目的是调查有宫颈锥切术病史并早期使用宫颈托治疗的患者的妊娠结局。在这项初步观察性研究中,我们纳入了21例患者,并评估了产科病史、放置宫颈托至分娩的间隔时间、分娩时的孕周、新生儿结局以及母婴住院天数。在21例患者的研究组中,20例为单胎妊娠,1例为双绒毛膜/双羊膜囊双胎妊娠。置入时,平均孕周为17 + 2(10 + 5 - 24 + 0)周,平均宫颈长度为19(4 - 36)mm。6例患者在置入时出现宫颈漏斗形成,平均漏斗宽度为19.7(10 - 38)mm,漏斗长度为19.9(10 - 37)mm。5例患者因早期自发性早产已至少失去一个孩子,另外5例患者既往至少有一次流产,目前已孕至34周以上分娩。分娩时的平均孕周为38(31 + 1 - 41 + 0)孕周,置入至分娩的平均间隔时间为145(87 - 182)天。我们的研究结果表明,对于因宫颈锥切术而早产风险较高的患者,早期放置宫颈托有有益作用。

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本文引用的文献

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Economic analysis of use of pessary to prevent preterm birth in women with multiple pregnancy (ProTWIN trial).使用子宫托预防多胎妊娠女性早产的经济学分析(ProTWIN试验)。
Ultrasound Obstet Gynecol. 2014 Sep;44(3):338-45. doi: 10.1002/uog.13432. Epub 2014 Aug 7.
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Impact of Patient and Procedure Mix on Finances of Perinatal Centres - Theoretical Models for Economic Strategies in Perinatal Centres.患者及手术组合对围产期中心财务状况的影响——围产期中心经济策略的理论模型
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