Garlets Zachary J, Nguyen John D, Stephenson Corey R J
University of Michigan, Department of Chemistry, 930 N. University Ave. Ann Arbor, Michigan 48109 (USA).
Isr J Chem. 2014 Apr 1;54(4):351-360. doi: 10.1002/ijch.201300136.
Visible-light photoredox catalysis has recently emerged as a viable alternative for radical reactions otherwise carried out with tin and boron reagents. It has been recognized that by merging photoredox catalysis with flow chemistry, slow reaction times, lower yields, and safety concerns may be obviated. While flow reactors have been successfully applied to reactions carried out with UV light, only recent developments have demonstrated the same potential of flow reactors for the improvement of visible-light-mediated reactions. This review examines the initial and continuing development of visible-light-mediated photoredox flow chemistry by exemplifying the benefits of flow chemistry compared with conventional batch techniques.
可见光光氧化还原催化最近已成为一种可行的替代方法，可用于原本使用锡和硼试剂进行的自由基反应。人们已经认识到，通过将光氧化还原催化与流动化学相结合，可以避免反应时间长、产率低和安全问题。虽然流动反应器已成功应用于紫外光反应，但直到最近的进展才证明流动反应器在改善可见光介导反应方面具有同样的潜力。本综述通过举例说明流动化学与传统间歇技术相比的优势，考察了可见光介导的光氧化还原流动化学的初步和持续发展。
