荚膜多糖与细胞包膜（糖）脂的遗传学
Genetics of Capsular Polysaccharides and Cell Envelope (Glyco)lipids.
作者信息
Daffé Mamadou, Crick Dean C, Jackson Mary
机构信息
CNRS, Institut de Pharmacologie et de Biologie Structurale, Département Mécanismes Moléculaires des Infections Mycobactériennes, and the Université de Toulouse Paul Sabatier, F-31077 Toulouse, France.
Mycobacteria Research Laboratories, Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins CO 80523-1682, USA.
出版信息
Microbiol Spectr. 2014;2(4). doi: 10.1128/microbiolspec.MGM2-0021-2013.
Abstract
This chapter summarizes what is currently known of the structures, physiological roles, involvement in pathogenicity and biogenesis of a variety of non-covalently bound cell envelope lipids and glycoconjugates of and other species. Topics addressed in this chapter include phospholipids; phosphatidylinositol mannosides; triglycerides; isoprenoids and related compounds (polyprenyl phosphate, menaquinones, carotenoids, non-carotenoid cyclic isoprenoids); acyltrehaloses (lipooligosaccharides, trehalose mono- and di-mycolates, sulfolipids, di- and poly-acyltrehaloses); mannosyl-beta-1-phosphomycoketides; glycopeptidolipids; phthiocerol dimycocerosates, para-hydroxybenzoic acids and phenolic glycolipids; mycobactins; mycolactones; and capsular polysaccharides.
摘要
本章总结了目前已知的各种非共价结合的细胞包膜脂质和糖缀合物的结构、生理作用、在致病性中的作用以及生物合成，这些物质存在于分枝杆菌属和其他相关物种中。本章涉及的主题包括磷脂；磷脂酰肌醇甘露糖苷；甘油三酯；类异戊二烯及相关化合物（聚异戊二烯磷酸、甲萘醌、类胡萝卜素、非类胡萝卜素环状异戊二烯）；酰基海藻糖（脂寡糖、海藻糖单和二霉菌酸酯、硫脂、二和多酰基海藻糖）；甘露糖基-β-1-磷酸霉菌酮酸酯；糖肽脂；邻苯二酚二霉菌酸酯、对羟基苯甲酸和酚糖脂；分枝杆菌素；分枝杆菌内酯；以及荚膜多糖。
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