Department of Surgical Oncology and Breast Unit, Ziekenhuis Rivierenland Tiel, The Netherlands.
Breast Unit, Ziekenhuis Rivierenland Tiel, The Netherlands.
Int J Surg. 2015 Jan;13:170-174. doi: 10.1016/j.ijsu.2014.11.050. Epub 2014 Dec 6.
It is not clear whether drains are necessary after breast cancer surgery. The purpose of this study was to compare seroma formation in patients that had postoperative drainage for 24 h with patients that had no drain after breast cancer surgery. In this retrospective cohort study 96 patients with a primary breast cancer were included. Between January 2009 and April 2011 44 patients had breast cancer surgery followed by postoperative drainage. Between May 2011 and February 2013 52 patients underwent breast cancer surgery without drainage. The operative procedures that were included were: axillary lymph node dissection, modified radical mastectomy or simple mastectomy±sentinel lymph node biopsy. There was no difference between both groups regarding frequency of seroma (84.6% versus 90.9%; p=0.290) and amount of seroma (540 ml versus 590 ml; p=0.446). Postoperative hospital stay was shorter in patients without drainage (2 versus 2.5 days; p=0.003). There was no difference between both groups in other secondary outcome measures. Modified radical mastectomy was an independent predictor of the amount of postoperative seroma (HR 0.039 [0.007-0.235]; p<0.001). These results suggest that there is no difference in seroma after breast cancer surgery between patients that had postoperative drainage and patients that had no postoperative drainage.
乳腺癌手术后是否需要引流尚不清楚。本研究旨在比较乳腺癌手术后引流 24 小时的患者与未引流患者的血清肿形成情况。在这项回顾性队列研究中，共纳入了 96 例原发性乳腺癌患者。2009 年 1 月至 2011 年 4 月期间，44 例患者接受了乳腺癌手术后引流。2011 年 5 月至 2013 年 2 月期间，52 例患者接受了乳腺癌手术但未引流。纳入的手术包括：腋窝淋巴结清扫术、改良根治性乳房切除术或单纯乳房切除术±前哨淋巴结活检。两组之间的血清肿发生率（84.6%与 90.9%；p=0.290）和血清肿量（540ml 与 590ml；p=0.446）没有差异。未引流患者的术后住院时间更短（2 天与 2.5 天；p=0.003）。两组在其他次要结局指标方面没有差异。改良根治性乳房切除术是术后血清肿量的独立预测因素（HR 0.039[0.007-0.235]；p<0.001）。这些结果表明，乳腺癌手术后引流与未引流患者之间的血清肿发生率没有差异。
