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Comparative antibacterial activity of the new cephalosporin cefcanel against anaerobic bacteria.

作者信息

Nord C E, Lindmark A, Persson I

机构信息

Department of Microbiology, Huddinge University Hospital, Karolinska Institute, Stockholm, Sweden.

出版信息

Eur J Clin Microbiol Infect Dis. 1989 Jun;8(6):550-1. doi: 10.1007/BF01967478.

DOI:10.1007/BF01967478
PMID:2548866
Abstract

The activity of cefcanel against anaerobic cocci, Clostridium perfringens, Bacteroides fragilis, Bacteroides spp. and fusobacteria was determined by the agar dilution method and compared with the activity of cefaclor, cephalexin, cefadroxil, phenoxymethylpenicillin and ampicillin. Cefcanel showed good activity against Clostridium perfringens, Bacteroides spp. and fusobacteria (MIC90 = 1-4 mg/l). Against anaerobic cocci its MIC90 value was 16 mg/l, and against Bacteroides fragilis, 32 mg/l. Cefcanel has an antibacterial activity that warrants investigation in clinical trials.

摘要

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本文引用的文献

1
Susceptibility to beta-lactam antibiotics and production of beta-lactamase in Bacteroides fragilis.脆弱拟杆菌对β-内酰胺类抗生素的敏感性及β-内酰胺酶的产生
Med Microbiol Immunol. 1977 Oct 7;163(3):183-94. doi: 10.1007/BF02126677.
2
Antibiotic susceptibility of anaerobic bacteria with special reference to Bacteroides fragilis.厌氧菌的抗生素敏感性,特别提及脆弱拟杆菌
Scand J Infect Dis Suppl. 1979(19):17-25.