Nickols-Richardson Sharon M, Piehowski Kathryn E, Metzgar Catherine J, Miller Debra L, Preston Amy G
Department of Food Science and Human Nutrition, The University of Illinois, Urbana-Champaign, 260A Bevier Hall, 905 S. Goodwin Ave.Urbana, IL 61801 USA.
Dietitian, 924 Washington St. SE, Albuquerque, NM 87108 USA.
Nutr Res Pract. 2014 Dec;8(6):695-704. doi: 10.4162/nrp.2014.8.6.695. Epub 2014 Nov 5.
BACKGROUND/OBJECTIVES: The type of sweet snack incorporated into an energy-restricted diet (ERD) may produce differential effects on metabolic improvements associated with body weight (BW) loss. This study compared effects of incorporating either twice daily energy-controlled dark chocolate snacks plus once daily sugar-free cocoa beverage (DC) to non-chocolate snacks plus sugar-free non-cocoa beverage (NC) into an ERD on BW loss and metabolic outcomes.
MATERIALS/METHODS: In an 18-week randomized comparative trial, 60 overweight/obese premenopausal women were assigned to DC (n = 30) or NC group (n = 30). Dietary intake was measured at baseline and week 18, and BW, anthropometrics, blood pressure (BP) and serum glucose, insulin and lipid concentrations were measured at baseline, and weeks 6, 12 and 18. Data were analyzed using repeated measures ANOVA.
Using intention-to-treat analysis, women in DC and NC groups reduced energy intake (both P < 0.001) and lost 4.4 ± 0.6 kg and 5.0 ± 0.9 kg (both P < 0.001), respectively. Both groups lowered systolic and diastolic BP [DC = 2.7 (P < 0.05), 2.7 (P < 0.01); NC = 3.4 (P < 0.01), 4.2 (P < 0.01) mmHg, respectively]. Glucose and insulin concentrations decreased by 0.72 mmol/L (P < 0.001) and 13.20 pmol/L (P < 0.01) in DC group and by 0.83 mmol/L (P < 0.001) and 13.20 pmol/L (P < 0.01), respectively, in NC group. Total cholesterol increased in NC group (P < 0.05), with no significant lipid changes in DC group. There were no significant differences in biomarker outcomes between groups.
Overweight/obese premenopausal women following an 18-week ERD that included either DC or NC sweet snack and sugar-free beverage lost equivalent amounts of BW and improved BP measurements and glucose and insulin concentrations.
背景/目的:纳入能量限制饮食(ERD)中的甜味零食类型可能对与体重(BW)减轻相关的代谢改善产生不同影响。本研究比较了在能量限制饮食中,每天两次摄入能量控制的黑巧克力零食加每天一次无糖可可饮料(DC)与非巧克力零食加无糖非可可饮料(NC)对体重减轻和代谢结果的影响。
材料/方法:在一项为期18周的随机对照试验中,60名超重/肥胖的绝经前女性被分配到DC组(n = 30)或NC组(n = 30)。在基线和第18周测量饮食摄入量,并在基线、第6周、第12周和第18周测量体重、人体测量学指标、血压(BP)以及血清葡萄糖、胰岛素和脂质浓度。使用重复测量方差分析对数据进行分析。
采用意向性分析,DC组和NC组女性的能量摄入量均减少(均P < 0.001),体重分别减轻4.4±0.6 kg和5.0±0.9 kg(均P < 0.001)。两组的收缩压和舒张压均降低[DC组分别为2.7(P < 0.05)、2.7(P < 0.01)mmHg;NC组分别为3.4(P < 0.01)、4.2(P < 0.01)mmHg]。DC组的葡萄糖和胰岛素浓度分别降低0.72 mmol/L(P < 0.001)和13.20 pmol/L(P < 0.01),NC组分别降低0.83 mmol/L(P < 0.001)和13.20 pmol/L(P < 0.01)。NC组的总胆固醇升高(P < 0.05),DC组的脂质无显著变化。两组之间的生物标志物结果无显著差异。
超重/肥胖的绝经前女性在进行为期18周的能量限制饮食时,无论摄入DC或NC甜味零食和无糖饮料,体重减轻量相当,血压测量值、葡萄糖和胰岛素浓度均得到改善。