Hammel I, Elmalek M, Castel M, Kalina M
Department of Pathology, Sackler School o Medicine, Tel-Aviv University, Israel.
Histochemistry. 1989;91(6):527-30. doi: 10.1007/BF00492527.
Variability in gold bead distribution between individual cells was demonstrated in both pituitary melanotrophic cells immunocytochemically reacted for ACTH and in neurohypophysial terminals reacted for oxytocin-neurophysin. Gold beads were confined to the secretory granules compartment of both tissues. Density of gold beads in melanotrophic cells reacted for ACTH varied from 100-480 gold beads/microns 2. A much narrower range of gold beads distribution (460-900 gold beads/microns 2) was observed in axons of the neurohypophysis reacted with anti-oxytocin-neurophysin. These results indicate that the labeling density varies from cell to cell (as well as axon terminals) within morphologically homogeneous populations. Thus, it may reflect certain physiological differences between cells. A suggestion is being made that mean gold bead density coefficient of variation should be calculated by comparison between individual cells.
在经促肾上腺皮质激素免疫细胞化学反应的垂体促黑素细胞以及经抗催产素 - 神经垂体素反应的神经垂体终末中，均证实了单个细胞之间金珠分布的变异性。金珠局限于两种组织的分泌颗粒区室。经促肾上腺皮质激素反应的促黑素细胞中金珠密度在100 - 480个金珠/微米²之间变化。在与抗催产素 - 神经垂体素反应的神经垂体轴突中观察到金珠分布范围要窄得多（460 - 900个金珠/微米²）。这些结果表明，在形态学上均一的群体中，标记密度在细胞之间（以及轴突终末之间）存在差异。因此，它可能反映了细胞之间某些生理差异。有人建议通过单个细胞之间的比较来计算平均金珠密度变异系数。
