McDonald G S, Courtney M G, Shattock A G, Weir D G
Department of Histopathology, Trinity College, Dublin, Ireland.
Liver. 1989 Aug;9(4):223-8. doi: 10.1111/j.1600-0676.1989.tb00403.x.
The case of a young man with hepatitis A and a chronic course is presented. The patient received a short course of steroid therapy for recurrence of symptoms following acute hepatitis A. Thereafter, liver enzymes have remained marginally elevated for 4 years and annual liver biopsies have shown evidence of chronicity. HAV IgM Ab persisted for 1034 days with subsequent development of HAV IgG Ab. The possibility of other viruses in the aetiology and the role of steroids in the development of chronicity are discussed.
本文报告了一例患有甲型肝炎且病程呈慢性的年轻男性病例。该患者在甲型肝炎急性期症状复发后接受了短期类固醇治疗。此后，肝酶持续轻度升高达4年，每年的肝脏活检均显示有慢性病变的证据。甲型肝炎IgM抗体持续存在1034天，随后出现甲型肝炎IgG抗体。文中讨论了病因中其他病毒的可能性以及类固醇在慢性化发展中的作用。
