Wellcome Trust - Medical Research Council Cambridge Stem Cell Institute, Anne McLaren Laboratory for Regenerative Medicine and Department of Surgery, University of Cambridge, Cambridge CB2 0QQ, UK.
Department of Genetics and The Human Genetics Institute of New Jersey, Rutgers, The State University of New Jersey, Piscataway, NJ 08854-8009, USA.
Stem Cell Reports. 2014 Dec 9;3(6):931-9. doi: 10.1016/j.stemcr.2014.11.006.
There is growing recognition of the potential value of human induced pluripotent stem cells (hiPSC) for understanding disease and identifying drugs targets. This has been reflected in the establishment of multiple large-scale hiPSC initiatives worldwide. Representatives of these met recently at a workshop supported by the Welcome Trust in the UK and in a focus session at the 2014 ISSCR annual meeting in Vancouver. The purpose was to discuss strategies for making thousands of hiPSC lines widely available with as few restrictions as possible while retaining financial viability and donor privacy. The outcome of these discussions is described here.
人们越来越认识到人类诱导多能干细胞（hiPSC）在理解疾病和确定药物靶点方面的潜在价值。这反映在全球范围内建立了多个大型 hiPSC 计划。这些代表最近在英国惠康信托基金会（Welcome Trust）支持的一次研讨会上以及在 2014 年温哥华 ISSCR 年会上的一个重点会议上进行了会晤。会议目的是讨论如何在保留财务可行性和捐赠者隐私的情况下，制定策略，尽可能广泛地提供数千种 hiPSC 系，同时限制条件尽可能少。这些讨论的结果在此处描述。
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