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情绪障碍的结构与短期稳定性:一种维度方法

The structure and short-term stability of the emotional disorders: a dimensional approach.

作者信息

Kotov R, Perlman G, Gámez W, Watson D

机构信息

Department of Psychiatry,Stony Brook University,Stony Brook,New York,USA.

Department of Psychology,University of Iowa,Iowa City,IA,USA.

出版信息

Psychol Med. 2015 Jun;45(8):1687-98. doi: 10.1017/S0033291714002815. Epub 2014 Dec 12.

Abstract

BACKGROUND

Factor-analytic studies have found that depressive, bipolar, post-traumatic, obsessive-compulsive, and anxiety disorders - jointly referred to as the emotional disorders - form an internalizing spectrum that includes distress and fear subfactors. However, placement of some disorders is uncertain. Also, prior research analysed dichotomous interview-based diagnoses or dimensional self-report measures. We investigated this structure using a third-generation measure - the Interview for Mood and Anxiety Symptoms (IMAS) - that combines strengths of a clinical interview with dimensional assessment.

METHOD

The interview was administered to 385 students and 288 psychiatric out-patients. Participants were reinterviewed 2 months later.

RESULTS

Exploratory and confirmatory factor analyses identified three factors: distress (depression, generalized anxiety, post-traumatic stress, irritability, and panic syndrome); fear (social anxiety, agoraphobia, specific phobia, and obsessive-compulsive); and bipolar (mania and obsessive-compulsive). The structure was consistent over time and across samples, except that panic and agoraphobia had higher factor loadings in patients. Longitudinal analyses revealed high temporal stability of the factors (test-retest r = 0.72 to 0.87), but also substantial disorder-specific stability.

CONCLUSIONS

This investigation - which bridges diagnostic and self-report studies - found three subfactors of internalizing psychopathology. It provided support for a new subfactor, clarified the placement of obsessive-compulsive and bipolar disorders, and demonstrated that this model generalizes across populations. The accumulating research suggests the need to recognize formally the close links among the emotional disorders, as well as empirical clusters within this spectrum. The IMAS demonstrated strong psychometric properties and can be useful for various research and clinical applications by providing dimensional, interview-based assessment of the emotional disorders.

摘要

背景

因素分析研究发现,抑郁、双相、创伤后、强迫和焦虑障碍——统称为情感障碍——形成了一个内化谱系,其中包括痛苦和恐惧子因素。然而,一些障碍的归属尚不确定。此外,先前的研究分析了基于访谈的二分法诊断或维度自评量表。我们使用第三代测量工具——情绪与焦虑症状访谈(IMAS)——对这一结构进行了调查,该工具结合了临床访谈和维度评估的优势。

方法

对385名学生和288名精神科门诊患者进行了访谈。2个月后对参与者进行了再次访谈。

结果

探索性和验证性因素分析确定了三个因素:痛苦(抑郁、广泛性焦虑、创伤后应激、易怒和惊恐综合征);恐惧(社交焦虑、广场恐惧症、特定恐惧症和强迫症);以及双相(躁狂症和强迫症)。除惊恐和广场恐惧症在患者中的因素负荷较高外,该结构在不同时间和样本中保持一致。纵向分析显示这些因素具有较高的时间稳定性(重测相关系数r = 0.72至0.87),但也存在显著的疾病特异性稳定性。

结论

这项跨越诊断和自评研究的调查发现了内化精神病理学的三个子因素。它为一个新的子因素提供了支持,明确了强迫症和双相障碍的归属,并证明该模型适用于不同人群。越来越多的研究表明,需要正式认识到情感障碍之间的紧密联系,以及该谱系内的实证聚类。IMAS表现出强大的心理测量特性,通过提供基于访谈的情感障碍维度评估,可用于各种研究和临床应用。

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