Greenhalgh David G
From the Shriners Hospitals for Children Northern California, Sacramento; Firefighters Regional Burn Center at University of California, Davis; and Department of Surgery, University of California, Davis.
J Burn Care Res. 2015 Mar-Apr;36(2):247-57. doi: 10.1097/BCR.0000000000000224.
There is at least a temporary loss of skin pigmentation with all but first-degree burns. Commonly, pigment changes persist for months, and sometimes, permanent changes in skin color add to the ultimate change in appearance that commonly affects burn patients. There are many different treatment modalities for the treatment of pigment changes, but most of them have little scientific basis and often lead to disappointing results. The purpose of this review is to discuss the molecular and cellular mechanisms of skin pigmentation, mechanisms of repigmentation after burns, treatment options for dealing with pigmentation changes, and advice for dealing with the sun after burn injury.
除一度烧伤外，所有烧伤都会导致至少暂时性的皮肤色素沉着丧失。通常，色素变化会持续数月，有时，皮肤颜色的永久性变化会加剧烧伤患者外观上的最终改变。治疗色素变化有许多不同的治疗方式，但其中大多数几乎没有科学依据，而且往往导致令人失望的结果。这篇综述的目的是讨论皮肤色素沉着的分子和细胞机制、烧伤后色素再沉着的机制、应对色素沉着变化的治疗选择以及烧伤后防晒建议。
