Bauman Jessica R, Temel Jennifer S
From Massachusetts General Hospital Cancer Center, Boston, Massachusetts.
J Natl Compr Canc Netw. 2014 Dec;12(12):1763-71; quiz 1771. doi: 10.6004/jnccn.2014.0177.
The past decade has brought forth innovative research that questions the traditional oncology care model for patients with advanced cancer. Through integrating palliative care (PC) early into the disease course for patients with a poor-prognosis cancer, 3 seminal studies showed improvements in outcomes, ranging from quality of life, mood, patient satisfaction, prognostic understanding, health service use, and possibly survival. The results of these paradigm-changing studies generate questions about the mechanisms through which early PC improves patient outcomes and about how best to disseminate early PC models. This article reviews the 3 studies, examines challenges to conducting PC research, and considers future directions in the field.
在过去十年中,出现了一些创新性研究,对晚期癌症患者的传统肿瘤护理模式提出了质疑。通过将姑息治疗(PC)早期纳入预后不良癌症患者的病程中,三项开创性研究表明,在生活质量、情绪、患者满意度、预后理解、医疗服务利用以及可能的生存率等方面,结果都有所改善。这些改变范式的研究结果引发了关于早期姑息治疗改善患者预后的机制以及如何最好地推广早期姑息治疗模式的问题。本文回顾了这三项研究,探讨了开展姑息治疗研究的挑战,并考虑了该领域的未来发展方向。