获得性免疫缺陷综合征患者与对照组的血浆脂肪酸水平。
Plasma fatty acid levels in patients with acquired immune deficiency syndrome and in controls.
作者信息
Bégin M E, Manku M S, Horrobin D F
机构信息
Efamol Research Institute, Kentville, Nova Scotia, Canada.
出版信息
Prostaglandins Leukot Essent Fatty Acids. 1989 Aug;37(2):135-7. doi: 10.1016/0952-3278(89)90110-5.
Polyunsaturated fatty acids (PUFAs) are known to modulate the immune system in vivo and to inactivate envelope viruses in vitro. Patients with AIDS had low total plasma lipid levels and low levels of a number of individual fatty acids. However, the C20 and C22 essential fatty acids of the n-3 series were selectively and highly significantly reduced. Normalization of these fatty acid levels in AIDS patients may be a worthwhile therapeutic aim.
多不饱和脂肪酸（PUFAs）已知在体内可调节免疫系统，并在体外使包膜病毒失活。艾滋病患者的血浆总脂质水平较低，且多种个别脂肪酸水平也较低。然而，n-3系列的C20和C22必需脂肪酸选择性地且高度显著降低。使艾滋病患者的这些脂肪酸水平恢复正常可能是一个值得追求的治疗目标。
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