Mitchell Alex J, Vancampfort Davy, De Hert Marc, Stubbs Brendon
Department of Cancer Studies & Molecular Medicine, Leicester Royal Infirmary, Leicester, LE1 5WW, UK.
Department of Neurosciences, KU Leuven-University of Leuven, UPC KU Leuven Campus Kortenberg, Leuvensesteenweg 517, B-3070 Kortenberg, Belgium; Department of Rehabilitation Sciences, KU Leuven-University of Leuven, Tervuursevest 101, B-3001 Leuven, Belgium.
Gen Hosp Psychiatry. 2015 Jan-Feb;37(1):14-23. doi: 10.1016/j.genhosppsych.2014.11.006. Epub 2014 Nov 21.
Prevalence rates of smoking in people with mental illness are high, and premature mortality attributed to tobacco related physical comorbidity is a major concern. We conducted a meta-analysis comparing rates of receipt of smoking cessation advice among people with and without mental illness.
Major electronic databases were searched from inception till August 2014 for studies comparing rates of receipt of smoking cessation advice of people with and without a mental illness. Two independent authors completed methodological appraisal and extracted data. A random-effects meta-analysis was utilized.
Seven studies of satisfactory methodological quality (n mental illness=68,811, n control=652,847) were included. Overall there was no significant difference in smoking cessation advice rates between those with and without a mental illness [relative risk (RR)=1.02, 95% confidence interval (CI)=0.94-1.11, n=721,658, Q=1421, P<.001]. Subgroup analyses demonstrated people with severe mental illness (SMI) received comparable rates of smoking cessation advice to those without SMI (RR=1.09, 95% CI=0.98-1.2, n=559,122). This remained true for people with schizophrenia (RR=1.09, 95% CI=0.68-1.70) and bipolar disorder (RR=1.14, 95% CI=0.85-1.5). People with non-SMIs were slightly more likely to receive smoking cessation advice (RR=1.16, 95% CI=1.04-1.30, Q=1364, P<.001, n=580,206).
People with SMI receive similar smoking cessation advice rates to people without mental illness, while those with non-SMI are slightly more likely to receive smoking cessation advice. While progress has been made, offering smoking cessation advice should receive a higher priority in everyday clinical practice for patients with a mental health diagnosis.
精神疾病患者的吸烟率很高,因烟草相关身体合并症导致的过早死亡是一个主要问题。我们进行了一项荟萃分析,比较了有精神疾病和无精神疾病人群接受戒烟建议的比例。
检索主要电子数据库,从建库至2014年8月,查找比较有精神疾病和无精神疾病人群接受戒烟建议比例的研究。两位独立作者完成方法学评估并提取数据。采用随机效应荟萃分析。
纳入了7项方法学质量良好的研究(精神疾病组n = 68,811,对照组n = 652,847)。总体而言,有精神疾病和无精神疾病人群的戒烟建议比例无显著差异[相对风险(RR)= 1.02,95%置信区间(CI)= 0.94 - 1.11,n = 721,658,Q = 1421,P <.001]。亚组分析表明,重度精神疾病(SMI)患者接受戒烟建议的比例与无SMI患者相当(RR = 1.09,95% CI = 0.98 - 1.2,n = 559,122)。精神分裂症患者(RR = 1.09,95% CI = 0.68 - 1.70)和双相情感障碍患者(RR = 1.14,95% CI = 0.85 - 1.5)也是如此。非SMI患者接受戒烟建议的可能性略高(RR = 1.16,95% CI = 1.04 - 1.