Gherman Vitalie, Tomuleasa Ciprian, Bungardean Catalina, Crisan Nicolae, Ona Victor-Dan, Feciche Bogdan, Irimie Alexandru, Coman Ioan
Research Center for Functional Genomics and Translational Medicine at the Iuliu Hatieganu, University of Medicine and Pharmacy, Cluj Napoca, Romania.
BMC Surg. 2014 Dec 15;14:107. doi: 10.1186/1471-2482-14-107.
Primary mesenchymal chondrosarcoma of the kidney is an extremely rare malignant tumor. To our best knowledge, only 9 such cases have been reported so far.
In the current paper, we present the case of a 67 year-old patient with recurrent left lumbar pain, increased fatigability and intermittent macroscopic hematuria. He underwent a surgical resection of the left kidney and left hemicolon.The pathological diagnosis was primary extraskeletal renal mesenchymal chondrosarcoma. Overall survival was 9 months, with pulmonary metastasis and local recurrence at 6 months. The management of the patient is described, from the initial differential diagnosis, after the first clinical examination to the surgical resection, with a special emphasis on the surgical procedures that were carried out.
Extraskeletal chondrosarcoma of primary origin in the kidney are extremely rare tumors with a highly malignant potential and very poor prognosis. Because the role of chemotherapy or radiation therapy has not been evaluated properly yet, we underline the importance of surgery in the management of such cases as the main and best approach to achieve clinical remission and long-term survival, provided the patient is referred to a surgical consult in time.
原发性肾间叶性软骨肉瘤是一种极其罕见的恶性肿瘤。据我们所知，迄今为止仅报道过9例此类病例。
在本文中，我们呈现了一名67岁患者的病例，该患者有反复的左腰部疼痛、疲劳感加重以及间歇性肉眼血尿。他接受了左肾和左半结肠的手术切除。病理诊断为原发性肾外间叶性软骨肉瘤。总生存期为9个月，6个月时出现肺转移和局部复发。描述了该患者从最初的鉴别诊断、首次临床检查后到手术切除的治疗过程，特别强调了所实施的手术步骤。
原发性起源于肾脏的肾外软骨肉瘤是极其罕见的肿瘤，具有高度恶性潜能且预后极差。由于化疗或放疗的作用尚未得到恰当评估，我们强调手术在这类病例管理中的重要性，即作为实现临床缓解和长期生存的主要且最佳方法，前提是患者能及时接受外科会诊。
