Hajmanoochehri Fatemeh, Mohammadi Navid, Rasoli Bashir, Ebtehaj Mehdi
Department of Pathology, Qazvin University of Medical Sciences, Qazvin, Iran E-mail :
Asian Pac J Cancer Prev. 2014;15(22):9649-54. doi: 10.7314/apjcp.2014.15.22.9649.
Polyps are common lesions in the gastrointestinal (GI) tract. Colon cancer is mostly a result of progression from polyps. The present study aimed to evaluate demographic, clinical, and histological characteristics of colorectal polyps in Iran, particularly neoplastic and advanced types.
Over a period of 10 years, specimens of all colorectal polyps obtained from colonoscopy were studied. The variables subjected to statistical analysis were age, sex, and the chief clinical complaint of the patients who underwent colonoscopy, their motivation, and the site, size, and histological types of detected polyps. The level of significance was set at p value<0.05.
Data were obtained from a total of 352 patients. No difference was seen between male and female patients regarding histological types. Only in nine patients was screening the reason for colonoscopy. Almost two-thirds (66.2%) of the polyps were neoplastic. Familial polyposis syndrome and inflammatory bowel disease were seen in 4.3% and 3.0% of the patients with neoplastic polyps, respectively. Sites of polyps were the sigmoid, rectum, and descending colon in 40.1%, 34.5%, and 17% of the cases, respectively. The advanced type made up 58.8% of neoplastic polyps. Only 3.6% of the patients undergoing colonoscopy in the study period had biopsied polyps.
No difference was observed between male and female patients in terms of overall incidence of polyps, histological and anatomical profiles, and mean age distribution. Anatomical and histological profiles agreed with the studies performed in areas with a low risk of colon cancer. The findings show that colonoscopy was not performed when it was necessary. A meaningful increase in the number polyp biopsy cases and a corresponding decrease in polyp size in the last few years of the study can be associated with the presence of more GI specialist clinicians in hospital centers, and this holds out much hope for the further improvement of the situation in the future.
息肉是胃肠道常见病变。结肠癌大多由息肉进展而来。本研究旨在评估伊朗结直肠息肉的人口统计学、临床和组织学特征，尤其是肿瘤性和进展期类型。
在10年期间，对结肠镜检查获取的所有结直肠息肉标本进行研究。进行统计分析的变量包括年龄、性别、接受结肠镜检查患者的主要临床主诉、其检查动机以及检测到的息肉的部位、大小和组织学类型。显著性水平设定为p值<0.05。
共获得352例患者的数据。男女患者在组织学类型方面无差异。仅9例患者因筛查而行结肠镜检查。几乎三分之二（66.2%）的息肉为肿瘤性。家族性息肉病综合征和炎症性肠病分别见于4.3%和3.0%的肿瘤性息肉患者。息肉部位分别在40.1%、34.5%和17%的病例中位于乙状结肠、直肠和降结肠。进展期类型占肿瘤性息肉的58.8%。在研究期间接受结肠镜检查的患者中，仅3.6%的患者对息肉进行了活检。
在息肉总体发病率、组织学和解剖学特征以及平均年龄分布方面，男女患者之间未观察到差异。解剖学和组织学特征与在结肠癌低风险地区进行的研究一致。研究结果表明，必要时未进行结肠镜检查。在研究的最后几年，息肉活检病例数有意义地增加以及息肉大小相应减小，这可能与医院中心有更多胃肠专科临床医生有关，这为未来情况的进一步改善带来了很大希望。
