Favre M, Obalek S, Jablonska S, Orth G
Unité de l'Institut National de la Santé et de la Recherche Médicale 190, Institut Pasteur, Paris, France.
J Virol. 1989 Nov;63(11):4909. doi: 10.1128/JVI.63.11.4909-.1989.
The cloning and characterization of the genome of human papillomavirus type 49 (HPV-49) is described. The viral DNA, which is most closely related to the DNAs of HPVs seen in patients with epidermodysplasia verruciformis, was aligned to the HPV-5 genome by electron microscopic analysis of heteroduplexes between the cloned viral DNAs.
本文描述了人乳头瘤病毒49型(HPV - 49)基因组的克隆与特性分析。通过对克隆病毒DNA之间的异源双链体进行电子显微镜分析,发现该病毒DNA与疣状表皮发育不良患者体内所见的HPV DNA最为密切相关,并将其与HPV - 5基因组进行了比对。