Lavigne Gilles J, Sessle Barry J
Pain Res Manag. 2015 Jan-Feb;20(1):7-14. doi: 10.1155/2015/785692. Epub 2014 Dec 18.
The year 2013-2014 has been designated the Global Year Against Orofacial Pain by the International Association for the Study of Pain. Accordingly, a multidisciplinary Canadian and international group of clinical, research and knowledge-transfer experts attended a workshop in Montreal, Quebec. The workshop had two aims: to identify new pathways for innovative diagnosis and management of chronic orofacial pain states; and to identify opportunities for further collaborative orofacial pain research and education in Canada. Three topics related to chronic orofacial pain were explored: biomarkers and pain signatures for chronic orofacial pain; misuse of analgesic and opioid pain medications for managing chronic orofacial pain; and complementary alternative medicine, topical agents and the role of stress in chronic orofacial pain. It was determined that further research is needed to: identify biomarkers of chronic orofacial post-traumatic neuropathic pain, with a focus on psychosocial, physiological and chemical-genetic factors; validate the short- and long-term safety (i.e., no harm to health, and avoidance of misuse and addiction) of opioid use for two distinct conditions (acute and chronic orofacial pain, respectively); and promote the use of topical medications as an alternative treatment in dentistry, and further document the benefits and safety of complementary and alternative medicine, including stress management, in dentistry. It was proposed that burning mouth syndrome, a painful condition that is not uncommon and affects mainly postmenopausal women, should receive particular attention.
2013 - 2014年被国际疼痛研究协会指定为“全球口面部疼痛防治年”。据此,一个由加拿大及国际临床、研究和知识传播专家组成的多学科团队参加了在魁北克省蒙特利尔市举办的研讨会。该研讨会有两个目标:确定慢性口面部疼痛状态创新诊断和管理的新途径;确定加拿大在口面部疼痛方面进一步开展合作研究与教育的机会。探讨了与慢性口面部疼痛相关的三个主题:慢性口面部疼痛的生物标志物和疼痛特征;用于管理慢性口面部疼痛的止痛和阿片类药物的误用;补充替代医学、局部用药以及压力在慢性口面部疼痛中的作用。会议确定需要进一步开展研究,以:确定慢性口面部创伤后神经性疼痛的生物标志物,重点关注心理社会、生理和化学遗传因素;分别针对两种不同情况(急性和慢性口面部疼痛)验证阿片类药物使用的短期和长期安全性(即对健康无害,避免误用和成瘾);促进局部用药在牙科中的替代治疗应用,并进一步记录补充替代医学(包括压力管理)在牙科中的益处和安全性。有人提议,灼口综合征这种并不罕见且主要影响绝经后女性的疼痛病症应得到特别关注。