性染色体驱动
Sex chromosome drive.
作者信息
Helleu Quentin, Gérard Pierre R, Montchamp-Moreau Catherine
机构信息
Laboratoire Évolution Génomes et Spéciation, CNRS UPR9034, Gif-sur-Yvette, France and Université Paris-Sud, Orsay, France.
出版信息
Cold Spring Harb Perspect Biol. 2014 Dec 18;7(2):a017616. doi: 10.1101/cshperspect.a017616.
Abstract
Sex chromosome drivers are selfish elements that subvert Mendel's first law of segregation and therefore are overrepresented among the products of meiosis. The sex-biased progeny produced then fuels an extended genetic conflict between the driver and the rest of the genome. Many examples of sex chromosome drive are known, but the occurrence of this phenomenon is probably largely underestimated because of the difficulty to detect it. Remarkably, nearly all sex chromosome drivers are found in two clades, Rodentia and Diptera. Although very little is known about the molecular and cellular mechanisms of drive, epigenetic processes such as chromatin regulation could be involved in many instances. Yet, its evolutionary consequences are far-reaching, from the evolution of mating systems and sex determination to the emergence of new species.
摘要
性染色体驱动因子是一类自私元件，它们破坏孟德尔第一分离定律，因此在减数分裂产物中占比过高。由此产生的性别偏向后代进而加剧了驱动因子与基因组其他部分之间的长期遗传冲突。已知许多性染色体驱动的例子，但由于难以检测，这种现象的实际发生率可能被大大低估了。值得注意的是，几乎所有的性染色体驱动因子都存在于两个进化枝中，即啮齿目和双翅目。尽管对驱动的分子和细胞机制了解甚少，但在许多情况下，诸如染色质调控等表观遗传过程可能与之有关。然而，其进化后果影响深远，从交配系统的进化、性别决定到新物种的出现。
相似文献
1
Sex chromosome drive.性染色体驱动
Cold Spring Harb Perspect Biol. 2014 Dec 18;7(2):a017616. doi: 10.1101/cshperspect.a017616.
2
Sex chromosome repeats tip the balance towards speciation.性染色体重复使物种形成倾向于平衡。
Mol Ecol. 2018 Oct;27(19):3783-3798. doi: 10.1111/mec.14577. Epub 2018 May 8.
3
Rapid rise and fall of selfish sex-ratio X chromosomes in Drosophila simulans: spatiotemporal analysis of phenotypic and molecular data.性比自私 X 染色体在果蝇 simulans 中的快速上升和下降：表型和分子数据的时空分析。
Mol Biol Evol. 2011 Sep;28(9):2461-70. doi: 10.1093/molbev/msr074. Epub 2011 Apr 15.
4
To what extent do different types of sex ratio distorters interfere?不同类型的性别比例扭曲者的干扰程度如何？
Evolution. 2004 Oct;58(10):2382-6. doi: 10.1111/j.0014-3820.2004.tb01612.x.
5
Genetic conflict and the origin of multigene families: implications for sex chromosome evolution.遗传冲突与多基因家族的起源：对性染色体进化的启示。
Proc Biol Sci. 2023 Nov 8;290(2010):20231823. doi: 10.1098/rspb.2023.1823. Epub 2023 Nov 1.
6
Phylogeography of sex ratio and multiple mating in stalk-eyed flies from southeast Asia.东南亚茎眼蝇性别比例与多次交配的系统发育地理学
Genetica. 2003 Jan;117(1):37-46. doi: 10.1023/a:1022360531703.
7
Sex chromosome meiotic drive in stalk-eyed flies.长脚蝇的性染色体减数分裂驱动
Genetics. 1997 Nov;147(3):1169-80. doi: 10.1093/genetics/147.3.1169.
8
Contrasting patterns of X-chromosome divergence underlie multiple sex-ratio polymorphisms in stalk-eyed flies.X染色体分化的对比模式是柄眼蝇多种性别比例多态性的基础。
J Evol Biol. 2017 Sep;30(9):1772-1784. doi: 10.1111/jeb.13140. Epub 2017 Aug 4.
9
Changing sex for selfish gain: B chromosomes of Lake Malawi cichlid fish.为了一己私利而改变性别：马拉维湖慈鲷鱼的 B 染色体。
Sci Rep. 2019 Dec 27;9(1):20213. doi: 10.1038/s41598-019-55774-8.
10
X-linked meiotic drive can boost population size and persistence.X 连锁减数分裂驱动可提高种群大小和持久性。
Genetics. 2021 Mar 3;217(1):1-11. doi: 10.1093/genetics/iyaa018.
引用本文的文献
1
Intrinsically weak sex chromosome drive through sequential asymmetric meiosis.通过连续不对称减数分裂产生的内在性弱性染色体驱动。
Sci Adv. 2025 May 9;11(19):eadv7089. doi: 10.1126/sciadv.adv7089. Epub 2025 May 7.
2
A selfish supergene causes meiotic drive through both sexes in .一个自私的超级基因在……中通过两性导致减数分裂驱动。 （你提供的原文不完整，这里是按照完整的翻译要求给出的译文，需结合完整原文理解准确意思）
Proc Natl Acad Sci U S A. 2025 Apr 29;122(17):e2421185122. doi: 10.1073/pnas.2421185122. Epub 2025 Apr 23.
3
Balancing selfing and outcrossing: the genetics and cell biology of nematodes with three sexual morphs.平衡自交与异交：具有三种性形态的线虫的遗传学与细胞生物学
Genetics. 2025 Feb 5;229(2). doi: 10.1093/genetics/iyae173.
4
Non-Mendelian transmission of X chromosomes: mechanisms and impact on sex ratios and population dynamics in different breeding systems.X 染色体的非孟德尔传递：在不同繁殖系统中对性别比例和种群动态的影响及其机制。
Biochem Soc Trans. 2024 Aug 28;52(4):1777-1784. doi: 10.1042/BST20231411.
5
An egg-sabotaging mechanism drives non-Mendelian transmission in mice.一种破坏卵子的机制驱动了小鼠的非孟德尔遗传。
Curr Biol. 2024 Sep 9;34(17):3845-3854.e4. doi: 10.1016/j.cub.2024.07.001. Epub 2024 Jul 26.
6
An egg sabotaging mechanism drives non-Mendelian transmission in mice.一种卵子破坏机制驱动小鼠中的非孟德尔遗传传递。
bioRxiv. 2024 Feb 23:2024.02.22.581453. doi: 10.1101/2024.02.22.581453.
7
Out with the old, in with the new: Meiotic driving of sex chromosome evolution.旧貌换新颜：减数分裂驱动性染色体进化。
Semin Cell Dev Biol. 2024 Nov-Dec;163:14-21. doi: 10.1016/j.semcdb.2024.04.004. Epub 2024 Apr 24.
8
Applications of advanced technologies for detecting genomic structural variation.先进技术在检测基因组结构变异中的应用。
Mutat Res Rev Mutat Res. 2023 Jul-Dec;792:108475. doi: 10.1016/j.mrrev.2023.108475. Epub 2023 Nov 4.
9
The Evolutionary History of Drosophila simulans Y Chromosomes Reveals Molecular Signatures of Resistance to Sex Ratio Meiotic Drive.《simulans 果蝇 Y 染色体的进化史揭示了对抗性别比例减数分裂驱动的分子特征》
Mol Biol Evol. 2023 Jul 5;40(7). doi: 10.1093/molbev/msad152.
10
Heterogeneous distribution of sex ratio distorters in natural populations of the isopod .自然种群中等足目动物性比偏移因子的不均匀分布。
Biol Lett. 2023 Jan;19(1):20220457. doi: 10.1098/rsbl.2022.0457. Epub 2023 Jan 11.
本文引用的文献
1
"SEX-RATIO" TRAIT, SEX COMPOSITION, AND RELATIVE ABUNDANCE IN DROSOPHILA PSEUDOOBSCURA.拟暗果蝇的“性比”性状、性别组成与相对丰度
Evolution. 1982 Jan;36(1):27-34. doi: 10.1111/j.1558-5646.1982.tb05006.x.
2
SELECTION AND THE "SEX-RATIO" POLYMORPHISM IN NATURAL POPULATIONS OF DROSOPHILA PSEUDOOBSCURA.伪黑腹果蝇自然种群中的选择与“性比”多态性
Evolution. 1996 Apr;50(2):787-794. doi: 10.1111/j.1558-5646.1996.tb03888.x.
3
DIVERGENCE OF MEIOTIC DRIVE-SUPPRESSION SYSTEMS AS AN EXPLANATION FOR SEX-BIASED HYBRID STERILITY AND INVIABILITY.减数分裂驱动抑制系统的分歧作为对性别偏向的杂种不育和 inviability 的一种解释。 （注：这里“inviability”可能是“胚胎发育不全”等类似意思，原文中该词拼写有误，推测可能是“inviability”，具体准确含义需结合更多背景知识确定）
Evolution. 1991 Mar;45(2):262-267. doi: 10.1111/j.1558-5646.1991.tb04401.x.
4
POLLEN PERFORMANCE AND SEX-RATIO EVOLUTION IN A DIOECIOUS PLANT.雌雄异株植物中的花粉表现与性别比例进化
Evolution. 1999 Aug;53(4):1028-1036. doi: 10.1111/j.1558-5646.1999.tb04518.x.
5
EVOLUTION OF DRIVING X CHROMOSOMES AND RESISTANCE FACTORS IN EXPERIMENTAL POPULATIONS OF DROSOPHILA SIMULANS.拟暗果蝇实验种群中驱动X染色体与抗性因子的进化
Evolution. 1999 Apr;53(2):506-517. doi: 10.1111/j.1558-5646.1999.tb03785.x.
6
SUPPRESSION OF SEX-RATIO MEIOTIC DRIVE AND THE MAINTENANCE OF Y-CHROMOSOME POLYMORPHISM IN DROSOPHILA.果蝇中性别比例减数分裂驱动的抑制与Y染色体多态性的维持
Evolution. 1999 Feb;53(1):164-174. doi: 10.1111/j.1558-5646.1999.tb05342.x.
7
MULTIPLE MATING AND THE "SEX-RATIO" TRAIT IN DROSOPHILA PSEUDOOBSCURA.拟暗果蝇的多次交配与“性比”性状
Evolution. 1981 Mar;35(2):275-281. doi: 10.1111/j.1558-5646.1981.tb04886.x.
8
Does polyandry control population sex ratio via regulation of a selfish gene?一妻多夫制是否通过调控自私基因来控制人口性别比例？
Proc Biol Sci. 2014 Apr 2;281(1783):20133259. doi: 10.1098/rspb.2013.3259. Print 2014 May 22.
9
XY females do better than the XX in the African pygmy mouse, Mus minutoides.在非洲侏儒小鼠（小埃及小鼠）中，XY雌性比XX雌性表现更好。
Evolution. 2014 Jul;68(7):2119-27. doi: 10.1111/evo.12387. Epub 2014 Mar 28.
10
Population dynamics of sperm and pollen killers.精子和花粉杀手的种群动态。
Theor Appl Genet. 1972 Jan;42(2):81-8. doi: 10.1007/BF00277948.
Zotero 插件