Andreotti Agda Marobo, Goiato Marcelo Coelho, Moreno Amália, Nobrega Adhara Smith, Pesqueira Aldiéris Alves, dos Santos Daniela Micheline
Araçatuba Dental School, São Paulo State University, Araçatuba, São Paulo, Brazil.
Int J Nanomedicine. 2014 Dec 10;9:5779-87. doi: 10.2147/IJN.S71533. eCollection 2014.
The aim of this study was to assess the effect of adding nanoparticles to N1 acrylic resin intended for artificial sclera, in terms of the color stability, microhardness, and flexural strength of the resin. Three hundred samples of N1 acrylic resin were used: 100 samples for color stability and microhardness tests (each test was performed on the opposite side of each sample), and 200 samples for flexural strength testing (100 samples before and after 1,008 hours of accelerated aging). Samples for each test were separated into ten groups (n=10), ie, without nanoparticles (control group) or with nanoparticles of zinc oxide, titanium dioxide (TiO₂), and barium sulfate at weight concentrations of 1%, 2%, and 2.5% (nanoparticle groups). Data were subjected to statistical analysis with nested analysis of variance and Tukey's test (P<0.05 significance level). Among the nanoparticle groups, the TiO₂ groups showed better color stability at all concentrations. Microhardness values increased after artificial aging, except for the control and zinc oxide groups. After aging, the 1%-2% TiO₂ groups had significantly higher microhardness values compared with the other nanoparticle groups. Before aging, there was a significant difference in flexural strength between the control and nanoparticle groups. After aging, the control and TiO₂ groups, regardless of concentration, showed the lowest flexural strength values. Incorporation of nanoparticles directly influenced the acrylic resin properties, with TiO₂ being the most influential nanoparticle in terms of the evaluated properties.
本研究的目的是评估在用于人工巩膜的N1丙烯酸树脂中添加纳米颗粒对树脂的颜色稳定性、显微硬度和弯曲强度的影响。使用了300个N1丙烯酸树脂样品：100个用于颜色稳定性和显微硬度测试（每个测试在每个样品的相对面进行），200个用于弯曲强度测试（100个在加速老化1008小时前后）。每个测试的样品分为十组（n = 10），即不添加纳米颗粒（对照组）或添加重量浓度为1%、2%和2.5%的氧化锌、二氧化钛（TiO₂）和硫酸钡纳米颗粒（纳米颗粒组）。数据采用嵌套方差分析和Tukey检验进行统计分析（显著性水平P<0.05）。在纳米颗粒组中，所有浓度的TiO₂组都表现出更好的颜色稳定性。人工老化后，除对照组和氧化锌组外，显微硬度值均有所增加。老化后，1%-2%的TiO₂组的显微硬度值明显高于其他纳米颗粒组。老化前，对照组和纳米颗粒组之间的弯曲强度存在显著差异。老化后，对照组和TiO₂组，无论浓度如何，弯曲强度值最低。纳米颗粒的加入直接影响了丙烯酸树脂的性能，就所评估的性能而言，TiO₂是最具影响力的纳米颗粒。
