Allison Ron R, Patel Rajen M, McLawhorn Robert A
21st Century Oncology, Inc., 801 WH Smith Blvd, Greenville, NC 27858, USA.
Future Oncol. 2014 Dec;10(15):2329-44. doi: 10.2217/fon.14.176.
Radiation therapy has become an ever more successful treatment for many cancer patients. This is due in large part from advances in physics including the expanded use of imaging protocols combined with ever more precise therapy devices such as linear and particle beam accelerators, all contributing to treatments with far fewer side effects. This paper will review current state-of-the-art physics maneuvers that minimize morbidity, such as intensity-modulated radiation therapy, volummetric arc therapy, image-guided radiation, radiosurgery and particle beam treatment. We will also highlight future physics enhancements on the horizon such as MRI during treatment and intensity-modulated hadron therapy, all with the continued goal of improved clinical outcomes.
放射治疗已成为许多癌症患者越来越成功的治疗方法。这在很大程度上归功于物理学的进步，包括成像方案的广泛应用以及线性和粒子束加速器等更加精确的治疗设备，所有这些都有助于减少副作用的治疗。本文将回顾当前最先进的物理技术，这些技术可将发病率降至最低，如调强放射治疗、容积弧形治疗、图像引导放射治疗、放射外科手术和粒子束治疗。我们还将重点介绍即将出现的未来物理技术改进，如治疗期间的磁共振成像和调强强子治疗，所有这些都以持续改善临床结果为目标。
