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Localization of the luminol-dependent chemiluminescence reaction in human granulocytes.

作者信息

Dahlgren C, Follin P, Johansson A, Lock R, Orselius K

机构信息

Department of Medical Microbiology, University of Linköping, Sweden.

出版信息

J Biolumin Chemilumin. 1989 Jul;4(1):263-6. doi: 10.1002/bio.1170040137.

DOI:10.1002/bio.1170040137
PMID:2552755
Abstract

The granulocyte luminol-dependent chemiluminescence (CL) reaction is linked to the enzyme myeloperoxidase reacting with products of the respiratory burst activation. The results presented in this paper, show that the light generated in granulocytes originate both from intracellular and extracellular reactions; however, depending on the stimulus used the one or the other will dominate the activity measured. Furthermore, lysosomal fusion is proposed to be required for the intracellular CL reaction.

摘要

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Localization of the luminol-dependent chemiluminescence reaction in human granulocytes.
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