感染人类免疫缺陷病毒的患者中出现的类似冠状病毒颗粒的机会性感染？
Opportunistic infections with coronavirus-like particles in patients infected with the human immunodeficiency virus?
作者信息
Eis-Hübinger A M, Stifter G, Schneweis K E
机构信息
Institut für Medizinische Mikrobiologie und Immunologie der Universität Bonn.
出版信息
Zentralbl Bakteriol. 1989 Sep;271(3):351-5. doi: 10.1016/s0934-8840(89)80034-9.
From 35 patients infected with Human Immunodeficiency Virus (HIV) and belonging to various risk groups, 60 stool specimens were examined for the presence of Coronavirus-like particles (CVLP) using electron microscopy. CVLP were detected in 5 (8%) stool samples from 5 different patients (14%). Only one of the patients had diarrhoea. The five patients with CVLP-positive stools were all at advanced stages of HIV infection. The remarkable discrepancy between our data and another study, reporting a rate of 50% CVLP-positive HIV patients, most of them persistently shedding the virus, is discussed.
从35名感染人类免疫缺陷病毒（HIV）且属于不同风险组的患者中，采集了60份粪便样本，使用电子显微镜检查是否存在冠状病毒样颗粒（CVLP）。在来自5名不同患者的5份（8%）粪便样本中检测到了CVLP（14%）。只有一名患者有腹泻症状。5名粪便CVLP呈阳性的患者均处于HIV感染晚期。本文讨论了我们的数据与另一项研究之间的显著差异，另一项研究报告CVLP阳性的HIV患者比例为50%，其中大多数患者持续排出该病毒。
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