手术材料：当前挑战与纳米解决方案
Surgical Materials: Current Challenges and Nano-enabled Solutions.
作者信息
Annabi Nasim, Tamayol Ali, Shin Su Ryon, Ghaemmaghami Amir M, Peppas Nicholas A, Khademhosseini Ali
机构信息
Center for Biomaterials Innovation, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA ; Harvard-MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, MA, USA ; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA, USA.
Center for Biomaterials Innovation, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA ; Harvard-MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, MA, USA.
出版信息
Nano Today. 2014 Oct 1;9(5):574-589. doi: 10.1016/j.nantod.2014.09.006.
Surgical adhesive biomaterials have emerged as substitutes to sutures and staples in many clinical applications. Nano-enabled materials containing nanoparticles or having a distinct nanotopography have been utilized for generation of a new class of surgical materials with enhanced functionality. In this review, the state of the art in the development of conventional surgical adhesive biomaterials is critically reviewed and their shortcomings are outlined. Recent advancements in generation of nano-enabled surgical materials with their potential future applications are discussed. This review will open new avenues for the innovative development of the next generation of tissue adhesives, hemostats, and sealants with enhanced functionality for various surgical applications.
在许多临床应用中，手术粘合生物材料已成为缝线和吻合钉的替代品。含有纳米颗粒或具有独特纳米拓扑结构的纳米材料已被用于制造具有增强功能的新型手术材料。在本综述中，对传统手术粘合生物材料的发展现状进行了批判性回顾，并概述了它们的缺点。讨论了纳米手术材料的最新进展及其潜在的未来应用。本综述将为新一代组织粘合剂、止血剂和密封剂的创新发展开辟新途径，这些产品将具有增强的功能，可用于各种手术应用。
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