London James, Tay Stan, Brown Brigid, Tancharoen Chasari
Department of Anaesthesia, Flinders Medical Centre, Bedford Park, South Australia, Australia.
Department of Anaesthesia, Royal Darwin Hospital, Tiwi, Northern Territory, Australia.
BMJ Case Rep. 2014 Dec 22;2014:bcr2014207314. doi: 10.1136/bcr-2014-207314.
Extravasation occurs frequently with intravenous infusions. In this case report we describe the occurrence of epidermal detachment and multiple cutaneous bullous eruptions in a patient's forearm following the extravasation of hydroxyethyl starch (Voluven, Fresenius Kabi)-a colloid solution derived from corn starch, which is used to replace lost blood volume. The patient's affected body surface area was managed under the direction of our plastic surgical team. Despite a prolonged admission in hospital from other perioperative complications, he made a full recovery and was successfully discharged home. The probable pathogenesis relevant to extravasation of Voluven is discussed; as well as its management principles.
静脉输注过程中渗漏现象经常发生。在本病例报告中，我们描述了一名患者前臂在羟乙基淀粉（万汶，费森尤斯卡比公司生产）——一种由玉米淀粉制成的胶体溶液，用于补充失血量——渗漏后出现表皮脱落和多处皮肤大疱性皮疹的情况。患者受影响的体表面积在我们整形外科团队的指导下进行处理。尽管因其他围手术期并发症住院时间延长，但他完全康复并成功出院。文中讨论了与万汶渗漏相关的可能发病机制及其处理原则。
