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容积调强弧形治疗患者特异性质量保证中计划复杂性与伽马指数分析之间的相关性研究。

A study on the correlation between plan complexity and gamma index analysis in patient specific quality assurance of volumetric modulated arc therapy.

作者信息

Rajasekaran Dhanabalan, Jeevanandam Prakash, Sukumar Prabakar, Ranganathan Arulpandiyan, Johnjothi Samdevakumar, Nagarajan Vivekanandan

机构信息

Department of Medical Physics, Cancer Institute (WIA), Chennai, India.

出版信息

Rep Pract Oncol Radiother. 2014 Sep 6;20(1):57-65. doi: 10.1016/j.rpor.2014.08.006. eCollection 2015 Jan.

Abstract

AIM

To evaluate the new Octavius 4D system for patient specific quality assurance and to study the correlation between plan complexity and gamma index analysis in patient specific quality assurance of VMAT using the Octavius 4D system.

BACKGROUND

McNiven (2010) proposed a study to evaluate the utility of a complexity metric, the Modulation Complexity Score, to evaluate the relationship of the metric with deliverability in IMRT.

MATERIALS AND METHODS

Evaluation of the Octavius 4D system was carried out by gamma evaluation of user defined MLC created patterns and AAPM TG 119 benchmark plans. The relationship between plan complexity expressed as Modulation Complexity Score (MCS) and the gamma index analysis was established by a planar and volumetric gamma analysis of 106 clinically approved VMAT patient plans of different sites.

RESULTS

Average volumetric 3D global gamma evaluation (3 mm/3%) results for the evaluation plans was 97.41% for 6 MV X-rays and 98.30% for 15 MV X-rays. Average MCS values for the head and neck, pelvic and thoracic plans were 0.2224, 0.3615 and 0.1874. Average volumetric 3D global gamma analysis (3 mm/3%) results for the head and neck, pelvic and thoracic VMAT plans were 95.45%, 97.51% and 96.98%, respectively. Out of 90 correlation analyses between the MCS and gamma passing rate, only 3 had the r value greater than 0.5.

CONCLUSIONS

The Octavius 4D system is a suitable device for patient specific pretreatment QA. Global and local gamma analysis results showed a weak correlation with the MCS.

摘要

目的

评估新型Octavius 4D系统用于患者特异性质量保证的情况,并研究在使用Octavius 4D系统进行容积调强放疗(VMAT)患者特异性质量保证时计划复杂性与伽马指数分析之间的相关性。

背景

McNiven(2010年)提出一项研究,以评估一种复杂性指标——调制复杂性评分,用于评估该指标与调强放疗(IMRT)可交付性之间的关系。

材料与方法

通过对用户定义的多叶准直器(MLC)创建的射野形状和美国医学物理师协会(AAPM)TG 119基准计划进行伽马评估,来评价Octavius 4D系统。通过对106例不同部位的临床批准的VMAT患者计划进行平面和容积伽马分析,建立以调制复杂性评分(MCS)表示的计划复杂性与伽马指数分析之间的关系。

结果

对于评估计划,6兆伏(MV)X射线的平均容积三维整体伽马评估(3毫米/3%)结果为97.41%,15 MV X射线为98.30%。头颈部、盆腔和胸部计划的平均MCS值分别为0.2224、0.3615和0.1874。头颈部、盆腔和胸部VMAT计划的平均容积三维整体伽马分析(3毫米/3%)结果分别为95.45%、97.51%和96.98%。在MCS与伽马通过率的90次相关性分析中,只有3次相关系数(r值)大于0.5。

结论

Octavius 4D系统是适用于患者特异性治疗前质量保证的设备。整体和局部伽马分析结果显示与MCS的相关性较弱。

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