Turk J Med Sci. 2014;44(2):208-11.
To reveal any correlation between cigarette smoke and malondialdehyde (MDA) values in the saliva fluid of subjects who are active smokers or nonsmoking subjects who are exposed to cigarette smoke in their environments.
Saliva samples were taken from 3 groups: a control group (group 1), a group inhaling smoke passively (group 2), and a test group (group 3) smoking 20 cigarettes per day; each group consisted of 20 members, giving a total sample of 60 people, aged 20 to 45 years. MDA, which is an indicator of lipid peroxidation, was measured via the colorimetric method.
Salivary MDA levels in smokers were found to be significantly higher compared to the control group and the group of passive smokers (P < 0.05). When compared with the control group, the MDA levels of passive smokers and active smokers were higher; when passive and active smokers were compared, the MDA levels of active smokers were higher. When all 3 groups were compared, the MDA levels in the control group (nonsmokers) were observed to be lower than the MDA level of the other 2 groups.
It was observed that lipid peroxidation, which is an indicator used to determine oxidative stress, and MDA level, which is a product of this reactive chain, are significantly higher in individuals who are smokers. Such a high level of MDA in passive smokers indicates that smoking also affects nonsmokers negatively.
揭示主动吸烟人群和处于吸烟环境中的被动吸烟人群唾液中丙二醛（MDA）值与吸烟之间的相关性。
采集 3 组唾液样本：对照组（第 1 组）、被动吸烟组（第 2 组）和每天吸烟 20 支的试验组（第 3 组）；每组 20 人，共 60 人，年龄 20 至 45 岁。通过比色法测量脂质过氧化的指标 MDA。
吸烟者的唾液 MDA 水平明显高于对照组和被动吸烟组（P<0.05）。与对照组相比，被动吸烟者和主动吸烟者的 MDA 水平更高；与主动吸烟者和被动吸烟者相比，主动吸烟者的 MDA 水平更高。当比较所有 3 组时，观察到对照组（不吸烟者）的 MDA 水平低于其他 2 组。
吸烟会导致脂质过氧化，这是衡量氧化应激的指标，MDA 是该反应链的产物，观察到吸烟个体的 MDA 水平明显更高。被动吸烟者 MDA 水平如此之高表明吸烟也会对不吸烟者产生负面影响。
