Neshat Fatemeh, Shirzaiy Masoomeh, Shademan Sepideh
Oral and Dental Diseases Research Center, School of Dentistry, Zahedan University of Medical Sciences, Zahedan, Iran.
Dentist, Private Practice, Zahedan, Iran.
Addict Health. 2020 Jul;12(3):216-224. doi: 10.22122/ahj.v12i3.276.
Environmental tobacco smoke (ETS) is one of the most toxic environmental exposures and passive smoking is an important general health problem. Children are the most vulnerable group to ETS exposure. This study aimed to compare the salivary total antioxidant capacity (TAC) and lipid peroxidation levels in passive smoking and nonsmoking adolescents aged 12-15 years.
This descriptive-analytical study was conducted on 80 adolescents aged 12-15 years. The case group included passive smokers and the control group comprised nonsmokers. These groups were age- and sex-matched ones. Unstimulated saliva of both groups was collected using the spitting method. Then, the salivary total antioxidant and lipid peroxidation levels were measured using the ferric-reducing antioxidant power (FRAP) and thiobarbituric acid reactive substances (TBARS) assays, respectively. The independent samples t-test was used for data comparison.
There was a significant difference in salivary total antioxidant levels between the case group (51.98 ± 88.97 µM) and the control group (174.35 ± 148.15 µM) (P = 0.003). There was no significant difference between the case group (0.97 ± 1.96) and the control group (0.81 ± 0.97) in lipid peroxidation levels (P = 0.542).
It seems that passive smoking can reduce the salivary TAC of adolescents, thereby threatening oral cavity health.
环境烟草烟雾（ETS）是毒性最强的环境暴露因素之一，被动吸烟是一个重要的公共卫生问题。儿童是最易受ETS暴露影响的群体。本研究旨在比较12至15岁被动吸烟和非吸烟青少年的唾液总抗氧化能力（TAC）和脂质过氧化水平。
本描述性分析研究对80名12至15岁的青少年进行。病例组包括被动吸烟者，对照组由非吸烟者组成。这些组在年龄和性别上相匹配。使用吐唾法收集两组的非刺激性唾液。然后，分别使用铁还原抗氧化能力（FRAP）和硫代巴比妥酸反应性物质（TBARS）测定法测量唾液总抗氧化剂和脂质过氧化水平。采用独立样本t检验进行数据比较。
病例组（51.98±88.97μM）和对照组（174.35±148.15μM）的唾液总抗氧化水平存在显著差异（P = 0.003）。病例组（0.97±1.96）和对照组（0.81±0.97）的脂质过氧化水平无显著差异（P = 0.542）。
被动吸烟似乎会降低青少年的唾液TAC，从而威胁口腔健康。
