Sharifi Hooman, Masjedi Mohammad Reza, Emami Habib, Ghanei Mostafa, Buist Sonia
Tobacco Prevention and Control Research Center, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Chronic Respiratory Diseases Research Center, National Research Institute of Tuberculosis and Lung Disease (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Int J Prev Med. 2014 Nov;5(11):1439-45.
Chronic obstructive pulmonary diseases (COPD) are planned to rank fifth in burden of disease and third with respect to mortality by 2020. Carrying out research regarding different aspects of COPD is mentioned as important health priorities by academic institutions and governments. The burden of lung disease (BOLD) Initiative was designed a decade ago to develop robust models that can be used to estimate the prevalence and current and future economic burden of COPD. The goal of the present project is to describe the prevalence and determining the causes and risk factors of COPD in the population of Tehran city.
This cross-sectional study follows a stratified cluster sampling strategy with proportional allocation within strata. The target population is all noninstitutionalized inhabitants, aged 18-40 in one group and over 40 in another, who inhabit in Tehran city. The stratification of the sample according to the 22 municipal districts of Tehran is incorporated in the sampling process. Proportional to the number of households in the 22 districts, the appropriate number of clusters is weighted according to each district. For each cluster, a team of three members approaches the index household, which is specified through the aforementioned random selection of clusters, and continues the enumeration in 10 neighbor households in a systematic manner.
As a study protocol, there are no specific results to present; our purpose is to share our design with the scientific body.
We expect that findings from the BOLD study in Tehran will show the status of COPD and its causes in the community.
慢性阻塞性肺疾病（COPD）预计到2020年在疾病负担方面将排名第五，在死亡率方面将排名第三。开展关于COPD不同方面的研究被学术机构和政府列为重要的卫生优先事项。肺病负担（BOLD）倡议于十年前启动，旨在开发强大的模型，用于估计COPD的患病率以及当前和未来的经济负担。本项目的目标是描述德黑兰市人群中COPD的患病率，并确定其病因和危险因素。
本横断面研究采用分层整群抽样策略，各层内按比例分配。目标人群是居住在德黑兰市的所有非机构化居民，一组年龄在18 - 40岁之间，另一组年龄在40岁以上。抽样过程中纳入了根据德黑兰22个市政区进行的样本分层。根据22个区的家庭数量，按比例对每个区的适当数量的群组进行加权。对于每个群组，由三名成员组成的团队接近通过上述随机选择群组确定的指标家庭，并以系统的方式在10个相邻家庭中继续进行普查。
作为一项研究方案，目前没有具体结果可展示；我们的目的是与科学界分享我们的设计。
我们预计德黑兰BOLD研究的结果将显示社区中COPD的状况及其病因。
