Campbell J P
J R Coll Gen Pract. 1989 Jan;39(318):11-4.
The possible role of cows milk intolerance in the aetiology of infant colic was evaluated in 19 babies presenting to their health visitor or general practitioner in one town. Over a three week period a standard modified cows milk formula was compared with a soya milk formula on a double blind basis. The duration of colic symptoms was significantly reduced during the week on soya milk (P less than 0.01), with 11 out of 19 babies fulfilling the diagnostic criteria for cows milk intolerance. Four babies whose symptoms failed to improve either spontaneously or with soya milk were given a hydrolysed protein milk with a positive response in two, confirmed by challenge testing. Thus in 13 out of 19 babies (68%) the symptoms of infant colic resolved almost completely with dietary change.
在一个城镇中,对19名向健康访视员或全科医生求诊的婴儿,评估了牛奶不耐受在婴儿腹绞痛病因学中的可能作用。在三周时间里,以双盲方式将标准改良牛奶配方与豆奶配方进行了比较。在食用豆奶的那一周,腹绞痛症状的持续时间显著缩短(P小于0.01),19名婴儿中有11名符合牛奶不耐受的诊断标准。有4名婴儿的症状无论是自发还是食用豆奶后都未改善,给他们服用了水解蛋白奶,其中2名有阳性反应,经激发试验证实。因此,19名婴儿中有13名(68%)的婴儿腹绞痛症状通过饮食改变几乎完全缓解。