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一例发生于成人的肝母细胞瘤。

A case of hepatoblastoma occurring in an adult.

作者信息

Sugino K, Dohi K, Matsuyama T, Asahara T, Yamamoto M

机构信息

Second Department of Surgery, Hiroshima University School, Japan.

出版信息

Jpn J Surg. 1989 Jul;19(4):489-93. doi: 10.1007/BF02471634.

Abstract

We present herein a rare case of hepatoblastoma occurring in an adult male. The patient was 22 years old and his laboratory investigations on admission showed a marked elevation of alpha-fetoprotein in the serum. CT scan and other examinations revealed a primary tumor, 6.5 cm in size, in the left hepatic lobe with metastasis in the head of the pancreas. Thus left hepatic lobectomy and pancreaticoduodenectomy were performed, but metastasis to the right hepatic lobe, left lung and abdominal skin were found 2 months later. Despite repeated courses of chemotherapy with adriamycin and cisplatin, the patient died 9 months after his operation. Pathological findings revealed poorly differentiated type hepatoblastoma. A review of the literature revealed only twelve other such cases.

摘要

我们在此报告一例罕见的发生于成年男性的肝母细胞瘤病例。该患者22岁,入院时实验室检查显示血清甲胎蛋白显著升高。CT扫描及其他检查发现左肝叶有一个6.5厘米大小的原发性肿瘤,并伴有胰腺头部转移。因此,实施了左肝叶切除术和胰十二指肠切除术,但2个月后发现肿瘤转移至右肝叶、左肺和腹部皮肤。尽管反复使用阿霉素和顺铂进行化疗,患者术后9个月仍死亡。病理检查结果显示为低分化型肝母细胞瘤。文献回顾显示仅有另外12例此类病例。

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