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一名年轻患者的小脑共济失调:通往狼疮的罕见路径。

Cerebellar ataxia in a young patient: A rare path to lupus.

作者信息

Ghosh Kaushik, Chatterjee Atri, Ghosh Susmita, Chakraborty Sisir

机构信息

Department of Medicine, Malda Medical College, Kolkata, West Bengal, India.

Department of Neurology, Nilratan Sircar Medical College, Kolkata, West Bengal, India.

出版信息

J Neurosci Rural Pract. 2014 Nov;5(Suppl 1):S75-6. doi: 10.4103/0976-3147.145212.

Abstract

Cerebellar ataxia is a rare manifestation of neuropsychiatric systemic lupus erythematosus (SLE). Development of vasculitic infarcts in the cerebellum is the most plausible reason of this manifestation. We report the case of a patient who presented with characteristic skin rashes of lupus along with cerebellar signs. Imaging of brain in this patient revealed prominent cerebellar atrophy. She was treated with mycophenolate mofetil and oral corticosteroid, and there was no further progression of her neurological signs after the initiation of therapy. In the clinical context of varied presentations of neurolupus, this is one of the rare sightings and our treatment protocol holds promise as first-line therapy in future.

摘要

小脑共济失调是神经精神性系统性红斑狼疮(SLE)的一种罕见表现。小脑血管炎性梗死的发生是这种表现最合理的原因。我们报告一例患者,其出现狼疮特征性皮疹及小脑体征。该患者脑部影像学检查显示明显的小脑萎缩。她接受了霉酚酸酯和口服糖皮质激素治疗,治疗开始后其神经体征未进一步进展。在神经狼疮表现多样的临床背景下,这是罕见病例之一,我们的治疗方案有望成为未来的一线治疗方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa35/4271393/5fe8ce52e08a/JNRP-5-75-g002.jpg

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