Singh R R, Prasad K, Kumar A, Misra A, Padmakumar K, Malaviya A N
Department of Medicine, All India Institute of Medical Sciences, New Delhi.
Ann Rheum Dis. 1988 Nov;47(11):954-6. doi: 10.1136/ard.47.11.954.
Three patients presented with cerebellar ataxia among 350 cases of systemic lupus erythematosus (SLE) seen over the last 14 years. Cerebellar signs were unilateral in one and bilateral in the other two patients. Other neurological findings were present in all three patients. One initially presented with only cerebellar ataxia; other features of SLE appeared a few years later. Lupus anticoagulant test was positive in one patient. Corticosteroids given in the early stages appeared to benefit these patients by ameliorating cerebellar dysfunction.
在过去14年中诊治的350例系统性红斑狼疮(SLE)患者中,有3例出现小脑性共济失调。1例患者的小脑体征为单侧性,另外2例为双侧性。所有3例患者均有其他神经系统表现。1例最初仅表现为小脑性共济失调,数年后出现SLE的其他特征。1例患者狼疮抗凝物检测呈阳性。早期给予的皮质类固醇似乎通过改善小脑功能障碍使这些患者获益。