De Pasquale Concetta, Veroux Massimiliano, Indelicato Luisa, Sinagra Nunzia, Giaquinta Alessia, Fornaro Michele, Veroux Pierfrancesco, Pistorio Maria L
Concetta De Pasquale, Massimiliano Veroux, Luisa Indelicato, Nunzia Sinagra, Alessia Giaquinta, Pierfrancesco Veroux, Maria L Pistorio, Vascular Surgery and Organ Transplant Unit, Department of Surgery, Transplantation and Advanced Technologies, University Hospital of Catania, 95124 Catania, Italy.
World J Transplant. 2014 Dec 24;4(4):267-75. doi: 10.5500/wjt.v4.i4.267.
Renal transplantation is a well established treatment for end-stage renal disease, allowing most patients to return to a satisfactory quality of life. Studies have identified many problems that may affect adaptation to the transplanted condition and post-operative compliance. The psychological implications of transplantation have important consequences even on strictly physical aspects. Organ transplantation is very challenging for the patient and acts as an intense stressor stimulus to which the patient reacts with neurotransmitter and endocrine-metabolic changes. Transplantation can result in a psychosomatic crisis that requires the patient to mobilize all bio-psycho-social resources during the process of adaptation to the new foreign organ which may result in an alteration in self-representation and identity, with possible psychopathologic repercussions. These reactions are feasible in mental disorders, e.g., post-traumatic stress disorder, adjustment disorder, and psychosomatic disorders. In organ transplantation, the fruitful collaboration between professionals with diverse scientific expertise, calls for both a guarantee for mental health and greater effectiveness in challenging treatments for a viable association between patients, family members and doctors. Integrated and multidisciplinary care should include uniform criteria and procedures for standard assessments, for patient autonomy, adherence to therapy, new coping strategies and the adoption of more appropriate lifestyles.
肾移植是终末期肾病的一种成熟治疗方法,能让大多数患者恢复到令人满意的生活质量。研究已经确定了许多可能影响对移植状态的适应和术后依从性的问题。移植的心理影响甚至在严格的身体方面也有重要后果。器官移植对患者来说极具挑战性,是一种强烈的应激源刺激,患者会通过神经递质和内分泌代谢变化做出反应。移植可能导致身心危机,在适应新的外来器官的过程中,患者需要调动所有生物 - 心理 - 社会资源,这可能会导致自我认知和身份认同的改变,并可能产生精神病理后果。这些反应在精神障碍中是可能出现的,例如创伤后应激障碍、适应障碍和身心障碍。在器官移植中,具有不同科学专业知识的专业人员之间富有成效的合作,既需要保障心理健康,又需要在针对患者、家庭成员和医生之间可行关联的具有挑战性的治疗中提高有效性。综合和多学科护理应包括用于标准评估、患者自主性、坚持治疗、新的应对策略以及采用更合适生活方式的统一标准和程序。