Narchi Hassib, Kochiyil Jose, Al Hamad Sania, Yasin Javed, Laleye Louis, Al Dhaheri Aisha
Paediatr Int Child Health. 2015 Feb;35(1):36-43. doi: 10.1179/2046905514Y.0000000144.
Despite living in a sunny country, hypovitaminosis D is common in women of reproductive age in Al Ain, United Arab Emirates (UAE).
To establish the prevalence of hypovitaminosis D in adolescent female Emirati nationals and its risk factors.
This was an analytical prospective cohort study of 350 female Emirati nationals aged 11-18 years attending public schools in Al Ain. Socio-economic status, diet and amount of sun exposure were evaluated by face-to-face interviews. Serum total 25 (OH) vitamin D (D2 + D3) levels were measured by electrochemiluminescence assay. The prevalence of hypovitaminosis D was calculated and the association with risk factors analysed.
Data were complete for 293 girls. Only one girl [prevalence 0.3%, 95% confidence interval (CI) 0.01-1.9] had vitamin D sufficiency (serum vitamin D levels >75 nmol/L). Three girls (1.0%, 95% CI 0.2-2.9) had vitamin D insufficiency (50-75 nmol/L), 58 (19.8%, 95% CI 15.0-25.5) were deficient (27.5-50 nmol/L) and 231 (78.8%, 95% CI 68.9-89.6) had severe deficiency (<27.5 nmol/L). Serum vitamin D levels declined between the ages of 11 and 13 years before progressively rising until the age of 18 years but without regaining the levels they were at the age of 11. There was no statistically significant difference between the vitamin D status groups in age, body mass index, accommodation type, family income, percentage of surface area unexposed to the sun when outdoors, consumption of oily fish or total vitamin D intake.
The finding of a high prevalence of hypovitaminosis D in adolescent females in UAE is of serious concern for their health and that of their infants during their reproductive lives. Adolescent girls with a similar social and cultural background currently living in less sunny, industrialised countries might also be at risk.
尽管生活在阳光充足的国家，但阿拉伯联合酋长国（阿联酋）艾因市育龄妇女维生素D缺乏症却很常见。
确定阿联酋青少年女性维生素D缺乏症的患病率及其危险因素。
这是一项对350名年龄在11至18岁、就读于艾因市公立学校的阿联酋女性国民进行的分析性前瞻性队列研究。通过面对面访谈评估社会经济状况、饮食和日照量。采用电化学发光法测定血清总25（OH）维生素D（D2 + D3）水平。计算维生素D缺乏症的患病率，并分析其与危险因素的关联。
293名女孩的数据完整。只有一名女孩[患病率0.3%，95%置信区间（CI）0.01 - 1.9]维生素D充足（血清维生素D水平>75 nmol/L）。三名女孩（1.0%，95% CI 0.2 - 2.9）维生素D不足（50 - 75 nmol/L），58名（19.8%，95% CI 15.0 - 25.5）缺乏（27.5 - 50 nmol/L），231名（78.8%，95% CI 68.9 - 89.6）严重缺乏（<27.5 nmol/L）。血清维生素D水平在11至13岁之间下降，然后逐渐上升直至18岁，但未恢复到11岁时的水平。维生素D状态组在年龄、体重指数、居住类型、家庭收入、户外未暴露于阳光的表面积百分比、油性鱼类消费量或总维生素D摄入量方面无统计学显著差异。
阿联酋青少年女性维生素D缺乏症患病率高这一发现，严重关乎她们及其生育期婴儿的健康。目前生活在阳光较少的工业化国家、具有相似社会文化背景的青春期女孩可能也面临风险。
