Phillips J Jane, Gordon Susan J
School of Public Health, Tropical Medicine and Rehabilitation Sciences, James Cook University, Townsville, Queensland, Australia.
J Pediatr Rehabil Med. 2014;7(4):361-72. doi: 10.3233/PRM-140306.
A systematic literature review was conducted to determine best practice conservative management of pediatric lymphoedema.
The PRISMA protocol was followed; a search of Ovid Medline, Cinahl and Scopus was conducted using the search terms children OR pediatric OR adolescent AND lymphoedema OR lymphedema. Studies about management or treatment of lymphoedema in children were included while studies about filariasis, imaging, pathology, secondary lymphoedema, surgical techniques, central lymphoedema and those with participants with a median age greater than 18 years were excluded.
Of 738 possible studies identified, eight studies were eligible for inclusion in the review: four case reports, two retrospective service reviews and two prospective studies investigating different interventions. All studies were rated using the NHMRC hierarchy of evidence and appraised by both authors using the McMaster University Critical Review Form. Studies were of low quality with poor descriptions of management, small sample size, unclear and inconsistent methodology and irreproducible outcome measures.
This review identified low level evidence to support the use of pneumatic compression in the management of pediatric lymphoedema. Further research is required to identify optimal parameters for application of pneumatic compression and to investigate the use of other interventions for conservative management of pediatric lymphoedema.
进行一项系统的文献综述,以确定小儿淋巴水肿保守治疗的最佳实践方法。
遵循PRISMA方案;使用检索词“儿童”或“儿科”或“青少年”以及“淋巴水肿”在Ovid Medline、Cinahl和Scopus数据库中进行检索。纳入关于儿童淋巴水肿管理或治疗的研究,排除关于丝虫病、影像学、病理学、继发性淋巴水肿、手术技术、中枢性淋巴水肿以及中位年龄大于18岁参与者的研究。
在识别出的738项可能的研究中,有8项研究符合纳入综述的条件:4项病例报告、2项回顾性服务综述以及2项调查不同干预措施的前瞻性研究。所有研究均根据澳大利亚国家卫生与医学研究委员会(NHMRC)的证据等级进行评级,并由两位作者使用麦克马斯特大学批判性综述表进行评估。这些研究质量较低,管理描述不佳,样本量小,方法不明确且不一致,结果测量不可重复。
本综述确定了低水平证据支持在小儿淋巴水肿管理中使用气压疗法。需要进一步研究以确定气压疗法应用的最佳参数,并研究其他保守治疗小儿淋巴水肿干预措施的使用情况。