Italian College of General Practitioners, Bari, Italy.
Department of Biosciences and Human Oncology (DIMO), Clinica Medica 'A. Murri', University of Bari Medical School, Policlinico Hospital, Bari, Italy.
Clin Nutr. 2015 Dec;34(6):1184-8. doi: 10.1016/j.clnu.2014.12.005. Epub 2014 Dec 17.
BACKGROUND & AIMS: Malnutrition is emerging as a multidimensional concern of ageing with a high prevalence among nursing home residents. This study investigated the extent of malnutrition among old subjects in family practice and its relationship with major complications.
Over 75 years old subjects (n = 274) filled the Mini Nutritional Assessment questionnaire. Appearance of major events in the following 6 months were registered.
MNA scored were 11.5 ± 3.1, with 175 (64%) subjects showing no malnutrition, 69 (25%) resulted at risk, and 30 (11%) malnourished. Within at risk group, 1.4% was resident, 7% bed rested, 8% had a history of major bone fracture, 33% was demented and 24.6% hospitalized at least once in the last year. Among malnourished patients, 10% was resident, ten bed rested with 70% showing multiple bedsores, 20% have had bone fractures, 60% were demented and 13% hospital admitted in the previous year. In over 90% of them, malnutrition had neither diagnosed nor considered before. During follow-up, a significantly higher number of major events including death occurred in the malnourished group. By multivariate logistic regression, n = 56 (20.4%) patients resulted at risk of major complications. The sensitivity of the questionnaire in identifying these patients was 84% with the cut-off value of 7 associated with the highest prediction (positive predictive value, 0.92; negative predictive value, 0.71) yielding a specificity of 92%.
The prevalence of malnutrition is high among older subjects in the setting of family practice. The Mini Nutritional Assessment allows to identify malnourished subjects better than BMI and effectively predicts the risk of major events.
营养不良正成为老龄化的一个多维度问题,在养老院居民中发病率很高。本研究调查了家庭实践中老年患者的营养不良程度及其与主要并发症的关系。
75 岁以上的患者(n=274)填写 Mini Nutritional Assessment 问卷。记录在接下来的 6 个月内出现的主要事件。
MNA 评分为 11.5±3.1,其中 175 例(64%)患者无营养不良,69 例(25%)存在营养不良风险,30 例(11%)营养不良。在营养不良风险组中,1.4%的患者为住院患者,7%的患者卧床休息,8%的患者有重大骨折史,33%的患者痴呆,24.6%的患者去年至少住院一次。在营养不良患者中,10%的患者为住院患者,10 例卧床休息,70%的患者有多处压疮,20%的患者有骨折,60%的患者痴呆,13%的患者去年住院。在他们中,超过 90%的患者之前没有被诊断或考虑营养不良。在随访期间,营养不良组发生重大事件(包括死亡)的人数明显更多。通过多变量逻辑回归,n=56(20.4%)患者存在主要并发症风险。该问卷识别这些患者的灵敏度为 84%,截断值为 7 与最高预测值(阳性预测值,0.92;阴性预测值,0.71)相关,特异性为 92%。
在家庭实践中,老年患者的营养不良患病率很高。Mini Nutritional Assessment 比 BMI 更能识别营养不良患者,并能有效预测重大事件的风险。