抗真菌药物治疗结节病：一项随访研究
Sarcoidosis treatment with antifungal medication: a follow-up.
作者信息
Terčelj Marjeta, Salobir Barbara, Zupancic Mirjana, Rylander Ragnar
机构信息
Clinic of Pulmonary Diseases and Allergy, University Medical Centre, Zaloska 7, 1000 Ljubljana, Slovenia.
Laboratory Department, Children's Hospital, University Medical Center, 1000 Ljubljana, Slovenia.
出版信息
Pulm Med. 2014;2014:739673. doi: 10.1155/2014/739673. Epub 2014 Dec 4.
INTRODUCTION
The aim of the study was to compare treatment of sarcoidosis with antifungal or corticosteroid medication.
METHODS
In patients with sarcoidosis antifungal medication (n = 29), corticosteroids (n = 21) or a combination (n = 27) was given. Nine patients allotted to antifungal medication were later given corticosteroids because of the lack of regression of the disease. X-ray scores for the severity of granuloma infiltration were determined. Chitotriosidase and angiotensin converting enzyme were determined. The time in months till remission was observed as well as the number of recurrences.
引言
本研究的目的是比较使用抗真菌药物或皮质类固醇药物治疗结节病的效果。
方法
给予结节病患者抗真菌药物（n = 29）、皮质类固醇药物（n = 21）或联合用药（n = 27）。由于病情未缓解，分配接受抗真菌药物治疗的9名患者后来改用皮质类固醇药物。测定肉芽肿浸润严重程度的X线评分。测定几丁质酶和血管紧张素转换酶。观察缓解所需的月数以及复发次数。
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