Fonseca Ana Glória, Dias Sara S, Baptista João Luis, Torgal Jorge
Public Health Department, Nova Medical School, Nova Lisbon University, Campo Mártires da Pátria 130, 1169-056 Lisbon, Portugal.
Public Health Department, Nova Medical School, Nova Lisbon University, Campo Mártires da Pátria 130, 1169-056 Lisbon, Portugal ; UIS-ESSLei-IPLeiria, Campus 2, Morro do Lena, Apartado 4137, 2411-901 Leiria, Portugal.
Malar Res Treat. 2014;2014:373029. doi: 10.1155/2014/373029. Epub 2014 Dec 7.
Background. Although eradicated in Portugal, malaria keeps taking its toll on travelers and migrants from endemic countries. Disease notification is mandatory but is compromised by underreporting. Methods. A retrospective study on malaria hospitalizations for 10 consecutive years (2000-2009) was conducted. Data on hospitalizations and notifications were obtained from Central Administration of Health System and Health Protection Agency, respectively. For data selection ICD-9 CM and ICD-10 were used: codes 084(*), 647.4, and B50-B54. Variables were gender, age, agent and origin of infection, length of stay (LOS), lethality, and comorbidities. Analysis included description, hypothesis testing, and regression. Results. There were 2003 malaria hospitalizations and 480 notified hospitalized cases, mainly in young male adults. P. falciparum was the main agent of infection acquired mainly in sub-Saharan Africa. Lethality was 1.95% and mean LOS was 8.09 days. Older age entailed longer LOS and increased lethality. Discussion. From 2000 to 2009, there were 2003 malaria hospitalizations with decreasing annual incidence, these numbers being remarkably higher than those notified. The national database of diagnosis related groups, reflecting hospitalizations on NHS hospitals, may be an unexplored complementary source for better estimates on imported malaria.
背景。尽管疟疾在葡萄牙已被根除，但它仍在对来自疟疾流行国家的旅行者和移民造成损害。疾病通报是强制性的，但存在报告不足的问题。方法。对连续10年（2000 - 2009年）的疟疾住院病例进行了回顾性研究。住院和通报的数据分别从卫生系统中央管理局和卫生保护局获取。数据选择使用国际疾病分类第九版临床修订本（ICD - 9 CM）和国际疾病分类第十版（ICD - 10）：编码084（*）、647.4以及B50 - B54。变量包括性别、年龄、感染病原体和感染源、住院时间（LOS）、致死率以及合并症。分析包括描述、假设检验和回归分析。结果。共有2003例疟疾住院病例，480例通报的住院病例，主要为年轻成年男性。恶性疟原虫是主要感染病原体，主要在撒哈拉以南非洲感染。致死率为1.95%，平均住院时间为8.09天。年龄较大者住院时间更长，致死率更高。讨论。2000年至2009年，有2003例疟疾住院病例，年发病率呈下降趋势，这些数字明显高于通报的数字。反映国民健康服务体系（NHS）医院住院情况的国家诊断相关组数据库，可能是一个未被探索的补充来源，有助于更好地估计输入性疟疾情况。
