Dong YanHong, Cheng Tuck Seng, Tsou Keith Yu Kei, Chan Qun Lin, Chen Christopher Li-Hsian
Department of Pharmacology, National University Health System, Yong Loo Lin School of Medicine, Clinical Research Centre, MD11, Level 5, No. 05-9, 10 Medical Drive, Singapore 117597 ; Centre for Healthy Brain Ageing and Dementia Collaborative Research Centre, UNSW Medicine, The University of New South Wales, Level 3, AGSM Building, Sydney, NSW 2052, Australia.
Department of Pharmacology, National University Health System, Yong Loo Lin School of Medicine, Clinical Research Centre, MD11, Level 5, No. 05-9, 10 Medical Drive, Singapore 117597.
ScientificWorldJournal. 2014;2014:302834. doi: 10.1155/2014/302834. Epub 2014 Dec 7.
The utility of informant AD8 for case finding of cognitive impairment at primary healthcare settings is unknown and therefore its feasibility and acceptability for targeted screening at a primary healthcare clinic should be investigated.
The informants of older adult patients attending a primary healthcare clinic in Singapore were administered the AD8. Positive screening findings were provided to patients' primary care physicians for referrals to specialist memory clinics. The acceptability of AD8 was evaluated by collecting feedbacks from the informants and primary care physicians.
205 patients and their informants were recruited. However, 6 (2.9%) informants were uncontactable, while the majority of the remaining 199 patients with completed AD8 (96.5%, n=192) found it acceptable where 59 (29.6%) patients were deemed cognitively impaired (AD8≥2). Clinicians (100%, n=5) found the AD8 helpful in facilitating referrals to memory clinics. However, most referral recommendations (81.4%, n=48) were declined by patients and/or informant due to limited insight of implications of cognitive impairment.
The AD8 can be easily administered and is well tolerated. It detected cognitive impairment in one-third of older adult patients and therefore may be useful for case finding of cognitive impairment in the primary healthcare.
在基层医疗环境中，知情者AD8问卷用于认知障碍病例筛查的效用尚不清楚，因此应调查其在基层医疗诊所进行针对性筛查的可行性和可接受性。
对在新加坡一家基层医疗诊所就诊的老年患者的知情者进行AD8问卷测试。将阳性筛查结果告知患者的初级保健医生，以便转介至专科记忆诊所。通过收集知情者和初级保健医生的反馈来评估AD8问卷的可接受性。
招募了205名患者及其知情者。然而，6名（2.9%）知情者无法取得联系，在其余199名完成AD8问卷测试的患者中，大多数（96.5%，n = 192）认为该问卷可接受，其中59名（29.6%）患者被判定为认知障碍（AD8评分≥2）。临床医生（100%，n = 5）认为AD8问卷有助于转介至记忆诊所。然而，由于患者和/或知情者对认知障碍影响的认识有限，大多数转介建议（81.4%，n = 48）被患者和/或知情者拒绝。
AD8问卷易于实施且耐受性良好。它在三分之一的老年患者中检测出认知障碍，因此可能有助于在基层医疗中进行认知障碍的病例筛查。
